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Paper Information

Journal:   JOURNAL OF ANIMAL BIOLOGY   SPRING 2015 , Volume 7 , Number 3; Page(s) 73 To 80.
 
Paper: 

HISTOLOGICAL STUDY OF THE EFFECT OF ETHANOL ON THE INJURED TENDON IN RAT

 
 
Author(s):  YAHYAEI B.*
 
* DEPARTMENT OF MEDICAL SCIENCES, SHAHROOD BRANCH, ISLAMIC AZAD UNIVERSITY, SHAHROOD, IRAN
 
Abstract: 

Ethanol has a suppressive effect on inflammation and immune responses and its impact has been studied in different regions of the body. But there is no useful information about ethanol effects on tendon structure. The aim of this study was to evaluate the histological effects of ethanol on rat tendon is injured. Twenty rats were randomly divided in two groups: ethanol and control. The amount of ethanol in combination with glucose in the drinking water of rats was gradually increased and was also used by them. After one week of use, the Achilles tendon of rats at each junction of the calcaneus injury was induced. In the fourth week, all rats were sacrificed and the injured tendon samples were collected and were examined histologically. Ethanol-induced increases Tenocyte with abnormal morphology, disruption and irregular collagen fibers toward increasing the number of Tenocyte and neovascularization was 3 weeks after tendon injury. Tendon in the ethanol group than the control group did not have any healing or improvement. The results of this study showed that ethanol causes delayed healing and tendon reformation.

 
Keyword(s): HISTOLOGY, TENDON, RAT, ETHANOL, TENOCYTE
 
References: 
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