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Paper Information

Journal:   JOURNAL OF FASA UNIVERSITY OF MEDICAL SCIENCES   SUMMER 2016 , Volume 6 , Number 2; Page(s) 221 To 226.
 
Paper: 

MOLECULAR DETECTION OF TYPE 1 FIMBRIAE-ENCODING GENE (FIMH) IN UROPATHOGENIC ESCHERICHIA COLI STRAINS ISOLATED FROM OUTPATIENTS WITH URINARY TRACT INFECTION

 
 
Author(s):  SHAMS N.*, JAYDARI A.
 
* DEPARTMENT OF MICROBIOLOGY, FACULTY OF VETERINARY MEDICINE, LORESTAN UNIVERSITY, KHORRAM ABAD, IRAN
 
Abstract: 

Background & Objective: Urinary Tract Infection (UTI) is one of the most common infections in all age groups. The majority of these infections are caused by Uropathogenic Escherichia coli (UPEC) strains. Colonization, attachment to uroepithelium, and the ability of UPEC to cause symptomatic UTI is mediated by adherence factors, such as type 1 fimbriae (fimH).
The objective of this study was to determine the frequency of type 1 fimbriae-encoding gene (fimH) among uropathogenic E. coli isolates from outpatients with UTI in Khorramabad.
Materials & Methods: This laboratory study carried out on 100 uropathogenic E. coli collected in the years 2012 and 2013 from outpatients with UTI in Khorramabad. All bacterial isolates were identified by standard laboratory methods and the fimH gene presence was detected using the PCR method.
Results: The fimH gene was amplified using specific primers and showed a band about 508 bp. The FimH gene was found in 26 isolates (26%) of the UPEC strains.
Conclusion: Although results of this study showed the presence of type 1 fimbriae-encoding gene (fimH) among uropathogenic E. coli isolates from outpatients with UTI, the high prevalence of isolates that do not encode fimH (74%) require further investigation to clarify the role of the other potential virulence factors in the pathogenesis of these isolates.

 
Keyword(s): URINARY TRACT INFECTIONS, UROPATHOGENIC ESCHERICHIA COLI, FIMH
 
 
References: 
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+ Click to Cite.
APA: Copy

SHAMS, N., & JAYDARI, A. (2016). MOLECULAR DETECTION OF TYPE 1 FIMBRIAE-ENCODING GENE (FIMH) IN UROPATHOGENIC ESCHERICHIA COLI STRAINS ISOLATED FROM OUTPATIENTS WITH URINARY TRACT INFECTION. JOURNAL OF FASA UNIVERSITY OF MEDICAL SCIENCES, 6(2), 221-226. https://www.sid.ir/en/journal/ViewPaper.aspx?id=511675



Vancouver: Copy

SHAMS N., JAYDARI A.. MOLECULAR DETECTION OF TYPE 1 FIMBRIAE-ENCODING GENE (FIMH) IN UROPATHOGENIC ESCHERICHIA COLI STRAINS ISOLATED FROM OUTPATIENTS WITH URINARY TRACT INFECTION. JOURNAL OF FASA UNIVERSITY OF MEDICAL SCIENCES. 2016 [cited 2021August02];6(2):221-226. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511675



IEEE: Copy

SHAMS, N., JAYDARI, A., 2016. MOLECULAR DETECTION OF TYPE 1 FIMBRIAE-ENCODING GENE (FIMH) IN UROPATHOGENIC ESCHERICHIA COLI STRAINS ISOLATED FROM OUTPATIENTS WITH URINARY TRACT INFECTION. JOURNAL OF FASA UNIVERSITY OF MEDICAL SCIENCES, [online] 6(2), pp.221-226. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511675.



 
 
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