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Paper Information

Journal:   IRANIAN JOURNAL OF PATHOLOGY (IJP)   SUMMER 2016 , Volume 11 , Number 3; Page(s) 255 To 260.
 
Paper: 

DEMSOPLASTIC SMALL ROUND CELL TUMOR: A DIAGNOSTIC AND THERAPEUTIC DILEMMA

 
 
Author(s):  SAFAVI MOEINADIN, SHAHRYARI JAHANBANOO, MOEINI AGHTAEI MOHAMMADMEHDI, NIKPOUR HOSSEIN*
 
* PATHOLOGY DEPARTMENT, AFZALIPOUR HOSPITAL, KERMAN UNIVERSITY OF MEDICAL SCIENCES, 22 BAHMAN BLVD., KERMAN, IRAN
 
Abstract: 

Desmoplastic small round cell tumor (DSCRT) is a rare variant of sarcoma with a highly aggressive behavior. It usually affects abdominal cavity and has a male predominance. Its correct diagnosis and treatment is sophisticated and requires an experienced multidisciplinary team. Hereby we present a 25 yrold man from Kerman Province in 2013 with abdominal mass and ascites who underwent sonograghy guided percutaneous needle biopsy which was misleading and inconclusive for diagnosis. Thus an open biopsy was fulfilled which revealed solid nests of small round cells with hyperchromatic nuclei and clear cytoplasm surrounded by a desmoplastic stroma suggestive for DSCRT. The diagnosis was confirmed by positive immunohitochemical reaction for cytokeratin, desmin and neuron specific enolase (NSE).Ultimately the patient underwent chemotherapy on the basis of P6 protocol without surgical debulking.Diagnosis and treatment of DSCRT could be a dilemma due to its rarity, various clinicopathologic mimickers and lack of a consensus about its management.

 
Keyword(s): DESMOPLASTIC SMALL ROUND CELL TUMOR, PATHOLOGY, CHEMOTHERAPY, NEEDLE BIOPSY
 
 
References: 
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APA: Copy

SAFAVI, M., & SHAHRYARI, J., & MOEINI AGHTAEI, M., & NIKPOUR, H. (2016). DEMSOPLASTIC SMALL ROUND CELL TUMOR: A DIAGNOSTIC AND THERAPEUTIC DILEMMA. IRANIAN JOURNAL OF PATHOLOGY (IJP), 11(3), 255-260. https://www.sid.ir/en/journal/ViewPaper.aspx?id=511621



Vancouver: Copy

SAFAVI MOEINADIN, SHAHRYARI JAHANBANOO, MOEINI AGHTAEI MOHAMMADMEHDI, NIKPOUR HOSSEIN. DEMSOPLASTIC SMALL ROUND CELL TUMOR: A DIAGNOSTIC AND THERAPEUTIC DILEMMA. IRANIAN JOURNAL OF PATHOLOGY (IJP). 2016 [cited 2021August06];11(3):255-260. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511621



IEEE: Copy

SAFAVI, M., SHAHRYARI, J., MOEINI AGHTAEI, M., NIKPOUR, H., 2016. DEMSOPLASTIC SMALL ROUND CELL TUMOR: A DIAGNOSTIC AND THERAPEUTIC DILEMMA. IRANIAN JOURNAL OF PATHOLOGY (IJP), [online] 11(3), pp.255-260. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511621.



 
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