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Paper Information

Journal:   JOURNAL OF FASA UNIVERSITY OF MEDICAL SCIENCES   SPRING 2016 , Volume 6 , Number 1; Page(s) 44 To 51.
 
Paper: 

ASSOCIATION OF BODY MASS INDEX WITH LEPTIN AND OTHER HORMONAL PARAMETERS IN WOMEN WITH UNEXPLAINED INFERTILITY AND FERTILE WOMEN

 
 
Author(s):  MASOMI M., TAFVIZI F.*
 
* DEPARTMENT OF BIOLOGY, PARAND BRANCH, ISLAMIC AZAD UNIVERSITY, PARAND, IRAN
 
Abstract: 

Background & objective: Obesity, as a major health concern in developed and developing countries, has many outcomes for people, among which is infertility in women. Therefore, this study was conducted to evaluate the correlation between the Body Mass Index (BMI) and the hormonal parameters in patients with unexplained infertility and normal subjects.
Materials & Methods: This case-control study was conducted on 40 patients with unexplained infertility and 30 fertile women with inclusion criteria of Follicle-stimulating hormone (FSH)<10, BMI<30, Anti-Müllerian hormone (AMH)
³1, normal Antral follicle count (AFC), and under the age of 35 years, after obtaining the informed consents, in Valiasr Fertility Clinic of Imam khomeyni Hospital in 2013-2014. On the third day of menstruation, the hormonal profile (including LH, FSH, Thyroid stimulating hormone (TSH), Prolactin (PRL), and AMH was measured and then, 5 ml of blood was taken. In addition, the serum leptin was measured using the leptin ELISA kit, and the correlation between BMI and all the hormones was evaluated.
Results: In all samples, the mean age, hormonal profile, and BMI had no statistically significant difference in the two groups. A direct and significant correlation was observed between BMI and leptin (p=0.003), and also between FSH and BMI (p=0.012) in the fertile women group.
Conclusion: Given the presence of a correlation between leptin and BMI, and the effect of leptin on ovulation, it is recommended that the infertile women maintain the BMI in the normal range, exercise and put the physical activity in their daily life schedules.

 
Keyword(s): BODY MASS INDEX (BMI), LEPTIN, UNEXPLAINED INFERTILITY
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

MASOMI, M., & TAFVIZI, F. (2016). ASSOCIATION OF BODY MASS INDEX WITH LEPTIN AND OTHER HORMONAL PARAMETERS IN WOMEN WITH UNEXPLAINED INFERTILITY AND FERTILE WOMEN. JOURNAL OF FASA UNIVERSITY OF MEDICAL SCIENCES, 6(1), 44-51. https://www.sid.ir/en/journal/ViewPaper.aspx?id=511468



Vancouver: Copy

MASOMI M., TAFVIZI F.. ASSOCIATION OF BODY MASS INDEX WITH LEPTIN AND OTHER HORMONAL PARAMETERS IN WOMEN WITH UNEXPLAINED INFERTILITY AND FERTILE WOMEN. JOURNAL OF FASA UNIVERSITY OF MEDICAL SCIENCES. 2016 [cited 2021August04];6(1):44-51. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511468



IEEE: Copy

MASOMI, M., TAFVIZI, F., 2016. ASSOCIATION OF BODY MASS INDEX WITH LEPTIN AND OTHER HORMONAL PARAMETERS IN WOMEN WITH UNEXPLAINED INFERTILITY AND FERTILE WOMEN. JOURNAL OF FASA UNIVERSITY OF MEDICAL SCIENCES, [online] 6(1), pp.44-51. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511468.



 
 
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