Paper Information

Journal:   THE JOURNAL OF NEPHRO-UROLOGY MONTHLY   2016 , Volume 8 , Number 2; Page(s) 0 To 0.
 
Paper: 

PREVALENCE AND MANAGEMENT OF LOWER URINARY TRACT SYMPTOMS RELATED TO BENIGN PROSTATIC OBSTRUCTION IN A CONTEMPORARY SERIES OF RENAL TRANSPLANT RECIPIENTS

 
 
Author(s):  ERGESI BJORN, WINKLER YVONNE, KISTLER THOMAS, GRIMM MARC OLIVER, JOHN HUBERT, HORSTMANN MARCUS*
 
* DEPARTMENT OF UROLOGY, JENA UNIVERSITY HOSPITAL, UNIVERSITY OF JENA, LESSINGSTR, JENA, GERMANY
 
Abstract: 

Background: The kidney is the most frequently transplanted human organ worldwide. In patients with end-stage renal failure, renal transplantation improves both quality of life and life expectancy. The current literature indicates that the numbers of renal recipients over 60 years of age has increased in recent years.
Objectives: To evaluate the prevalence and management of lower urinary tract symptoms (LUTS) related to benign prostatic obstruction (BPO) in a contemporary series of male renal transplant (RTx) recipients.
Materials and Methods: We retrospectively evaluated 150 consecutive transplant recipients at the University of Jena 12 months postoperatively for the presence and treatment of LUTS related to BPO.
Results: The mean age of the patients was 59 years (range 27 - 82 years). By 12 months postoperatively, 91% (n=137.150) were off dialysis with a functioning kidney graft. Two patients died during follow up. Six patients had undergone treatment for prostate cancer prior to RTx. Of the remaining 131 patients, 47% (n=62.131) were considered as patients with BPO 12 months after RTx. Six percent (n=8.131) of the patients experienced urinary retention due to BPO and 6% (n=8.131) had a transurethral resection of the prostate (TURP) during the first year after RTx. No major complications were observed in those patients. A significant increase was noted in the use of-blocker therapy after RTx (P=0.004).
Conclusions: We observed a high prevalence of LUTS related toBPOin our cohort of patients. Dueto the increasing age of transplant recipients, more attention should be paid to the evaluation and treatment of BPO prior to RTx.

 
Keyword(s): RENAL TRANSPLANTATION (RTX), BENIGN PROSTATIC OBSTRUCTION (BPO), LOWER URINARY TRACT SYMPTOMS (LUTS), TRANSURETHRAL RESECTION OF THE PROSTATE (TURP), ALPHA-BLOCKER TREATMENT, MEDICAL TREATMENT OF BPO
 
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