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Paper Information

Journal:   IRANIAN JOURNAL OF PATHOLOGY (IJP)   SPRING 2016 , Volume 11 , Number 2; Page(s) 155 To 160.
 
Paper: 

RAD51 EXPRESSION IN NASOPHARYNGEAL CARCINOMA AND ITS ASSOCIATION WITH TUMOR REDUCTION: A PRELIMINARY STUDY IN INDONESIA

 
 
Author(s):  CAHYANTI DIAN*, RACHMADI LISNAWATI, WULANI VALLY, ADHAM MARLINDA
 
* DEPARTMENT OF ANATOMICAL PATHOLOGY, FACULTY OF MEDICINE UNIVERSITAS INDONESIA/ CIPTO MANGUNKUSUMO HOSPITAL, JALAN SALEMBA RAYA 6, JAKARTA 10430
 
Abstract: 

Background: Overexpression of Rad51 protein in many tumor cells has been proven to increase radioresistance and can be related to the resistance of chemosensitivity of tumor cells. This preliminary study was conducted to determine the relationship between the Rad51 expression level in nasopharyngeal carcinoma and the response of the treatment based on the measurement of the tumor reduction.
Methods: Thirteen cases of the NPCs were analyzed. The expression levels of the Rad51 were examined from the pretreatment biopsies. Furthermore, tumor reductions were determined based on the change in sum longest diameter of the nasopharyngeal CT-scan before and after therapy.
Results: The expression level of the Rad51 was associated with the reduction of tumor mass. The P value was 0.049 and the correlation coefficient was 0.479.
Conclusion: The tumor cells Rad51 expression levels may affect the tumor reduction of NPC after the therapy.

 
Keyword(s): NASOPHARYNGEAL CARCINOMA, RAD51 EXPRESSION, TUMOR REDUCTION
 
 
References: 
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APA: Copy

CAHYANTI, D., & RACHMADI, L., & WULANI, V., & ADHAM, M. (2016). RAD51 EXPRESSION IN NASOPHARYNGEAL CARCINOMA AND ITS ASSOCIATION WITH TUMOR REDUCTION: A PRELIMINARY STUDY IN INDONESIA. IRANIAN JOURNAL OF PATHOLOGY (IJP), 11(2), 155-160. https://www.sid.ir/en/journal/ViewPaper.aspx?id=511346



Vancouver: Copy

CAHYANTI DIAN, RACHMADI LISNAWATI, WULANI VALLY, ADHAM MARLINDA. RAD51 EXPRESSION IN NASOPHARYNGEAL CARCINOMA AND ITS ASSOCIATION WITH TUMOR REDUCTION: A PRELIMINARY STUDY IN INDONESIA. IRANIAN JOURNAL OF PATHOLOGY (IJP). 2016 [cited 2021August01];11(2):155-160. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511346



IEEE: Copy

CAHYANTI, D., RACHMADI, L., WULANI, V., ADHAM, M., 2016. RAD51 EXPRESSION IN NASOPHARYNGEAL CARCINOMA AND ITS ASSOCIATION WITH TUMOR REDUCTION: A PRELIMINARY STUDY IN INDONESIA. IRANIAN JOURNAL OF PATHOLOGY (IJP), [online] 11(2), pp.155-160. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511346.



 
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