Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   JOURNAL OF MEDICINAL PLANTS   June 2004 , Volume 3 , Number 10; Page(s) 61 To 70.
 
Paper: 

EFFICACY OF AQUEOUS EXTRACT OF ECHIUM AMOENUM L. IN THE TREATMENT OF MILD TO MODERATE MAJOR DEPRESSIVE DISORDER: A RANDOMIZED DOUBLE BLIND CLINICAL TRIAL

 
 
Author(s):  Saiiah bargard M.*, ASADI S.M., AMINI HOMAYOUN, AKHOUNDZADEH S., SAIIAH M., KAMALINEZHAD M.
 
* Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran
 
Abstract: 
The aim of this study was to evaluate the efficacy and safety of a constant dose of aqueous extract of Echium amoenum. Thirty-five patients with mild to moderate major depressive disorder who had a score ³ 18 on the Hamilton Depression Rating Scale were enrolled in the study and randomly assigned to receive either placebo or 375mg of aqueous extract of Echinum amoenum. Patients were followed for 6 weeks. Efficacy was assessed by the Hamilton Depression Rating Scale, in week 0, 1, 2, 4, and 6. In the week 4 and 6, drug was superior to placebo. This difference was significant at the fourth week (p =0.018) and marginally non-significant at the sixth week. The extract of Echium amoenum did not cause more adverse effects than placebo during the study. It is concluded that the aqueous extract of Echium amoenum can be considered as an effective and safe treatment for major depressive disorder. However further studies in warranted.
 
Keyword(s): ECHIUM AMOENUM L., MAJOR DEPRESSIVE DISORDER
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 89
 
Latest on Blog
Enter SID Blog