Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   JOURNAL OF OPHTHALMIC AND VISION RESEARCH   2016 , Volume 11 , Number 2; Page(s) 153 To 158.
 
Paper: 

CORRELATIONS BETWEEN HISTOPATHOLOGIC CHANGES AND CLINICAL FEATURES IN PTERYGIA

 
DOI: 

10.4103/2008-322X.183917

 
Author(s):  SAFI HAMID*, KHEIRKHAH AHMAD, MAHBOD MIRGHOLAMREZA, MOLAEI SABER, HASHEMI HASSAN, JABBARVAND MAHMOUD
 
* SHAHID SADOUGHI HOSPITAL, SHAHID GHANDI BLVD, EBNE SINA AVE, YAZD 89158, IRAN
 
Abstract: 

Purpose: To investigate the correlations between clinical findings and histopathologic changes in eyes with pterygium.
Methods: This prospective study included 70 eyes with primary pterygia undergoing surgical excision.
Prior to surgery, clinical features of the pterygia including extension over the cornea, redness, fleshiness (based on obscuration of the underlying episcleral vessels), and obliteration of the plica semilunaris were determined. Postoperatively, pterygium specimens were examined by hematoxylin?eosin and trichrome staining to evaluate histopathologic characteristics including vascular density, leukocytic infiltration, stromal elastosis, stromal fibrosis and subepithelial fibrosis. Correlations between clinical findings and histopathologic changes were then investigated.
Results: There was a marginally significant correlation between the redness and the fleshiness of pterygium (P=0.06). Both redness and fleshiness of the pterygium had significant positive correlation with dimensions of the lesion over the cornea. Moreover, larger pterygia were associated with obliteration of the plica semilunaris. Pterygium redness showed a significant correlation with vascular density (P=0.04), and pterygium fleshiness had a significant correlation with stromal fibrosis (P=0.04). Pterygium dimensions over the cornea demonstrated a positive correlation with vascular density and a negative correlation with stromal elastosis.
Conclusion: Redness and fleshiness of pterygium were only marginally correlated with each other, and each one showed a correlation with different histopathologic features. Larger pterygia were associated with more significant changes at the clinical and histopathologic levels.

 
Keyword(s): ELASTOSIS, FIBROSIS, PTERYGIUM, VASCULAR DENSITY
 
 
References: 
  • Not Registered.
  •  
  •  
 
Citations: 
  • Not Registered.
 
+ Click to Cite.
APA: Copy

SAFI, H., & KHEIRKHAH, A., & MAHBOD, M., & MOLAEI, S., & HASHEMI, H., & JABBARVAND, M. (2016). CORRELATIONS BETWEEN HISTOPATHOLOGIC CHANGES AND CLINICAL FEATURES IN PTERYGIA. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, 11(2), 153-158. https://www.sid.ir/en/journal/ViewPaper.aspx?id=511121



Vancouver: Copy

SAFI HAMID, KHEIRKHAH AHMAD, MAHBOD MIRGHOLAMREZA, MOLAEI SABER, HASHEMI HASSAN, JABBARVAND MAHMOUD. CORRELATIONS BETWEEN HISTOPATHOLOGIC CHANGES AND CLINICAL FEATURES IN PTERYGIA. JOURNAL OF OPHTHALMIC AND VISION RESEARCH. 2016 [cited 2021August02];11(2):153-158. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511121



IEEE: Copy

SAFI, H., KHEIRKHAH, A., MAHBOD, M., MOLAEI, S., HASHEMI, H., JABBARVAND, M., 2016. CORRELATIONS BETWEEN HISTOPATHOLOGIC CHANGES AND CLINICAL FEATURES IN PTERYGIA. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, [online] 11(2), pp.153-158. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=511121.



 
  pdf-File
Yearly Visit 45
 
 
Latest on Blog
Enter SID Blog