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Paper Information

Journal:   ARCHIVES OF IRANIAN MEDICINE   JULY 2016 , Volume 19 , Number 7; Page(s) 465 To 469.
 
Paper: 

SINGLE VERSUS DOUBLE INTRAUTERINE INSEMINATION IN CONTROLLED OVARIAN HYPERSTIMULATION CYCLES: A RANDOMIZED TRIAL

 
DOI: 

0161907/AIM.004

 
Author(s):  ZAHIRI SOROURI ZIBA, RASHID SHOMALI ROMINA*, POURMARZI DAVOUD
 
* REPRODUCTIVE HEALTH RESEARCH CENTER, DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, ALZAHRA HOSPITAL, GUILAN UNIVERSITY OF MEDICAL SCIENCES, RASHT, IRAN
 
Abstract: 

BACKGROUND: There are many factors that affect intrauterine insemination (IUI) success rate and identifying those factors can be helpful. This study aimed to investigate the single versus double IUI in controlled ovarian hyperstimulation cycles.
METHODS: This is a randomized clinical trial with equal randomization (1:1) conducted on 580 women who underwent IUI in a private infertility clinic from May 2013 to November 2014 in Rasht, Iran. Women were randomly assigned to single (n=290) or double (n=290) IUI groups. Women in the single group underwent IUI performed 36 h after human chorionic gonadotropin (HCG) administration. Women in the double group underwent two IUIs performed 18 and 40 hours after HCG administration. The main outcome was clinical pregnancy confirmed by evidence of fetal cardiac activity. Data were analyzed by SPSS software. Comparisons of frequencies were done using the Fisher exact test and Chi-square test. For comparing means between the two groups, the independent t-test was used. The P-value < 0.05 was considered to indicate statistical significance.
RESULTS: Pregnancy rate was 11.7% (34.290) in the single IUI group and 13.4% (39.249) in the double IUI group. The difference between the two groups was not statistically significant (P=0.617, OR=1.17, 95% CI: 0.72-1.91). Also, we could not show significant difference between single and double IUI groups in different cause of infertility groups regarding the success rate.
CONCLUSION: Based on findings, double versus single IUI did not increase the pregnancy rate of IUI and further investigations are recommended.

 
Keyword(s): CONTROLLED OVARIAN HYPERSTIMULATION, INTRAUTERINE INSEMINATION, PREGNANCY RATE, SINGLE AND DOUBLE INSEMINATION
 
 
References: 
 
Citations: 
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APA: Copy

ZAHIRI SOROURI, Z., & RASHID SHOMALI, R., & POURMARZI, D. (2016). SINGLE VERSUS DOUBLE INTRAUTERINE INSEMINATION IN CONTROLLED OVARIAN HYPERSTIMULATION CYCLES: A RANDOMIZED TRIAL. ARCHIVES OF IRANIAN MEDICINE, 19(7), 465-469. https://www.sid.ir/en/journal/ViewPaper.aspx?id=510920



Vancouver: Copy

ZAHIRI SOROURI ZIBA, RASHID SHOMALI ROMINA, POURMARZI DAVOUD. SINGLE VERSUS DOUBLE INTRAUTERINE INSEMINATION IN CONTROLLED OVARIAN HYPERSTIMULATION CYCLES: A RANDOMIZED TRIAL. ARCHIVES OF IRANIAN MEDICINE. 2016 [cited 2021August02];19(7):465-469. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=510920



IEEE: Copy

ZAHIRI SOROURI, Z., RASHID SHOMALI, R., POURMARZI, D., 2016. SINGLE VERSUS DOUBLE INTRAUTERINE INSEMINATION IN CONTROLLED OVARIAN HYPERSTIMULATION CYCLES: A RANDOMIZED TRIAL. ARCHIVES OF IRANIAN MEDICINE, [online] 19(7), pp.465-469. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=510920.



 
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