Paper Information

Journal:   JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)   1ST WEEK AUGUST 2016 , Volume 34 , Number 385; Page(s) 629 To 636.
 
Paper: 

EVALUATION OF PROPHYLACTIC INJECTION OF TWO DOSES OF TRAMADOL ON HEART RATE AND BLOOD PRESSURE CHANGES COMPARED WITH CONTROL GROUP AFTER LARYNGOSCOPY AND INTUBATION

 
 
Author(s):  HONARMAND AZIM, SAFAVI MOHAMMAD REZA*, SOHRABI BEHNAZ
 
* ANESTHESIOLOGY AND CRITICAL CARE RESEARCH CENTRE, DEPARTMENT OF ANESTHESIOLOGY, SCHOOL OF MEDICINE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

Background: Laryngoscopy is an invasive technique which is associated with severe cardiovascular complications. This study compared the effects of two doses of tramadol hydrochloride (2mg/kg, 1mg/kg) on heart rate and blood pressure with control group after laryngoscopy and intubation in elective surgical patients.
Methods: In this clinical trial performed in 2015, 180 candidates in Kashani care center, Isfahan, Iran, were randomly divided to control (no drugs were used), tramadol 1mg/kg and tramadol 2mg/kg groups. Heart rate, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure were recorded immediately before, after, and 1, 3 and 5, 10 min after laryngoscopy. Data were analyzed using SPSS and ANOVA and Tukey post hoc tests.
Findings: There were significant differences in systolic, diastolic and mean arterial pressure between control group and two doses of tramadol (P<0.05). Also in heart rate the differences were significant. The incidence of hypertension, tachycardia, hypotension and bradycardia were less in two doses of tramadol.
Conclusion: Prescribing 2 mg/kg of tramadol causes more stable blood pressure and heart rate compared with control group.

 
Keyword(s): TRAMADOL, LARYNGOSCOPY, CARDIOVASCULAR COMPLICATION
 
References: 
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