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Journal:   IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)   MAY 2016 , Volume 10 , Number 3; Page(s) 126 To 134.
 
Paper: 

ASSOCIATION OF SERUM URIC ACID WITH CARDIOMETABOLIC RISK FACTORS AND METABOLIC SYNDROME IN IRANIAN ADOLESCENTS THE CASPIAN-III STUDY

 
 
Author(s):  SAFIRI SAEID, QORBANI MOSTAFA*, HESHMAT RAMIN, TAJBAKHSH RAMIN, ESLAMI SHAHR BABAKI AMIR, DJALALINIA SHIRIN, MOTLAGH MOHAMMAD ESMAEIL, TAJADINI MOHAMMAD HASAN, ASAYESH HAMID, SAFARI OMID, KELISHADI ROYA*
 
* RESEARCH INSTITUTE FOR PRIMORDIAL PREVENTION OF NONCOMMUNICABLE DISEASE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, HEZAR-JARIB AVE, ISFAHAN, IRAN
 
Abstract: 

Introduction: There is controversial evidence on association of serum acid uric (SUA) with cardio metabolic risk factors and metabolic syndrome in adults. This study aimed to investigate the associations of SUA levels, components of metabolic syndrome, and other cardiometabolic risk factors, in a nationally representative sample of Iranian adolescents.
Materials and Methods: This study included 132 participants whomet the criteria of metabolic syndrome and 235 participants without metabolic syndrome. The participants were grouped according to the tertiles of SUA. Metabolic syndrome was defined according to the Adult Treatment Panel III criteria modified for children and adolescents. The relationship between SUA and cardio metabolic risk factors and metabolic syndrome was assessed by multivariable logistic regression analysis.
Results: The mean age of the participants was 15.21 ± 2.35 years, with no significant difference between the boys and the girls. The participants whose SUA was categorized in the 2nd tertile and those falling into the 3rd tertile had significantly higher systolic blood pressure (P<.001) as compared with the lower tertile (s). A similar trend was documented for the overall high blood pressure.
Metabolic syndrome was associated with the 2nd and 3rd tertiles of SUA as compared to the lower tertile (s), in the adjusted model(P<.001), with the risk increasing by at least 2 times.
Conclusions: Our study showed that those adolescents with metabolic syndrome had higher SUA levels. Its association with some components of metabolic syndrome supports that SUA might be an additional component of metabolic syndrome even during adolescence.

 
Keyword(s): SERUM URIC ACID, METABOLIC SYNDROME, ADOLESCENTS, IRAN
 
 
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APA: Copy

SAFIRI, S., & QORBANI, M., & HESHMAT, R., & TAJBAKHSH, R., & ESLAMI SHAHR BABAKI, A., & DJALALINIA, S., & MOTLAGH, M., & TAJADINI, M., & ASAYESH, H., & SAFARI, O., & KELISHADI, R. (2016). ASSOCIATION OF SERUM URIC ACID WITH CARDIOMETABOLIC RISK FACTORS AND METABOLIC SYNDROME IN IRANIAN ADOLESCENTS THE CASPIAN-III STUDY. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), 10(3), 126-134. https://www.sid.ir/en/journal/ViewPaper.aspx?id=510641



Vancouver: Copy

SAFIRI SAEID, QORBANI MOSTAFA, HESHMAT RAMIN, TAJBAKHSH RAMIN, ESLAMI SHAHR BABAKI AMIR, DJALALINIA SHIRIN, MOTLAGH MOHAMMAD ESMAEIL, TAJADINI MOHAMMAD HASAN, ASAYESH HAMID, SAFARI OMID, KELISHADI ROYA. ASSOCIATION OF SERUM URIC ACID WITH CARDIOMETABOLIC RISK FACTORS AND METABOLIC SYNDROME IN IRANIAN ADOLESCENTS THE CASPIAN-III STUDY. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD). 2016 [cited 2021August04];10(3):126-134. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=510641



IEEE: Copy

SAFIRI, S., QORBANI, M., HESHMAT, R., TAJBAKHSH, R., ESLAMI SHAHR BABAKI, A., DJALALINIA, S., MOTLAGH, M., TAJADINI, M., ASAYESH, H., SAFARI, O., KELISHADI, R., 2016. ASSOCIATION OF SERUM URIC ACID WITH CARDIOMETABOLIC RISK FACTORS AND METABOLIC SYNDROME IN IRANIAN ADOLESCENTS THE CASPIAN-III STUDY. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), [online] 10(3), pp.126-134. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=510641.



 
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