Paper Information

Journal:   GOVARESH JOURNAL   FALL 2015 , Volume 20 , Number SUPPLEMENT; Page(s) 0 To 0.
 
Paper: 

CORNEAL ARCUS IN INDIVIDUALS LESS THAN 50 YEARS OLD WITH NON-ALCOHOLIC STEATOHEPATITIS SYNDROME, GORGAN CITY, 2014

 
 
Author(s):  BOROUMAND NEGAR, HOSSEINPOUR REZA, NOROUZI ALIREZA*
 
* 1GOLESTAN RESEARCH CENTER OF GASTEROENTROLOGY AND HEPATOLOGY (GRCGH),GOLESTAN UNIVERSITY OF MEDICAL SCIENCES (GOUMS)
 
Abstract: 

Introduction: Corneal arcus is the result of lipid deposition around the cornea. Non-alcoholic steatohepatitis (NASH) is a health issue with raising prevalence presented with elevated liver enzymes and ultrasound typical findings. This study was designed to assess the prevalence of corneal arcus in patients with NASH.
Methods: In this cross-sectional study, from March 2014 to February 2015; all patients younger than 50-years-old diagnosed as NASH (N=200) in the academic hospitals of Gorgan city, were recruited.
Diagnosis of NASH was based on the liver ultrasound reports and liver enzymes tests (ALT, AST). Ophthalmic examination with Slit-lamp was done to assess the presence of corneal arcus.
Results: Ninety one patients (45.5%) diagnosed as having the corneal arcus. A significant relationship was seen between the corneal arcus and smoking, opium consumption and the positive family history of NASH. After controlling the confounding variables) diabetes, hypertension, smoking, hyperlipidemia, age, gender, ethnicity and body mass index (, it was seen that a positive family history of fatty liver disease and ischemic heart disease are significantly associated with corneal arcus.
Conclusion: There was seen a high prevalence of corneal arcus in patients with NASH syndrome.

 
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