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Paper Information

Journal:   GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH   2016 , Volume 9 , Number 3; Page(s) 220 To 224.
 
Paper: 

PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT)

 
 
Author(s):  BRAGA ANTONIO COSTA*, VASCONCELOS CARLOS, BRAGA JORGE
 
* OBSTETRICS DEPARTMENT, CENTRO MATERNO INFANTIL DO NORTE - CENTRO HOSPITALAR DO PORTO (CHP), OPORTO, PORTUGAL
 
Abstract: 

Aim: The aim of this study was to review our experience with gestations in autoimmune hepatitis patients.
Background: There are only limited data describing pregnancy in patients with autoimmune hepatitis. Patients and methods: Retrospective analysis of pregnancies with autoimmune hepatitis followed in Centro Hospitalar do Porto, Portugal in the last ten years.
Results: We reported nine pregnancies in seven patients with autoimmune hepatitis. Two patients had documented liver cirrhosis prior to the pregnancy. In this study, 66.7% of patients were treated with azathioprine and 88.9% with prednisolone. Clinical improvements were observed in 11.1% of pregnancies and 22.2% exacerbations were diagnosed. There were six live births and two preterm deliveries (preterm delivery rate of 33%). We also report three first trimester miscarriages (early gestation miscarriage rate of 33%). There were no neonatal or maternal deaths.
Conclusion: The favorable obstetric outcome is a realistic expectation in patients with autoimmune hepatitis. Tight monitoring and control of asymptomatic and unpredictable exacerbations, which are unrelated to the severity of the underlying disease, are essential to the prognosis of the current pregnancy.

 
Keyword(s): HIGH-RISK PREGNANCY, LIVER DISORDER AND PREGNANCY, AZATHIOPRINE
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

BRAGA, A., & VASCONCELOS, C., & BRAGA, J. (2016). PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT). GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, 9(3), 220-224. https://www.sid.ir/en/journal/ViewPaper.aspx?id=509989



Vancouver: Copy

BRAGA ANTONIO COSTA, VASCONCELOS CARLOS, BRAGA JORGE. PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT). GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH. 2016 [cited 2021July25];9(3):220-224. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509989



IEEE: Copy

BRAGA, A., VASCONCELOS, C., BRAGA, J., 2016. PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT). GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, [online] 9(3), pp.220-224. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509989.



 
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