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Paper Information

Journal:   ANESTHESIOLOGY AND PAIN MEDICINE   JUNE 2016 , Volume 6 , Number 3; Page(s) 0 To 0.
 
Paper: 

CURRENT UNDERSTANDING ON PAIN MECHANISM IN MIGRAINE AND CLUSTER HEADACHE

 
 
Author(s):  BUTURE ALINA*, GOORIAH RUBESH, NIMERI RANDA, AHMED FAYYAZ
 
* DEPARTMENT OF NEUROLOGY, HULL ROYAL INFIRMARY, ANLABY ROAD, HULL HU3 2JZ, UK
 
Abstract: 

Context: Migraine and cluster headache are undoubtedly painful conditions. The respective pathogenesis of these two conditions is incompletely understood. In both cases, the treatments used have largely been empirical and have relied to a much lesser extent on our understanding of the mechanisms causing pain. We hereby review the pain mechanisms in migraine and cluster headache, two of the commonest primary headache disorders.
Evidence Acquisition: A review of the English literature was conducted by searching PubMed for studies on pain mechanism in migraine and cluster headache. We entered [migraine] and [pain mechanism] in Pubmed and 488 articles were obtained. Articles were then included according to their relevance to the topic. Similarly, [cluster headache] and [pain mechanism] revealed 79 search results.
Results: There is evidence that the trigeminovascular system and neurogenic inflammation play important roles, together with certain areas of the brain, leading to these conditions beingtermed‘neurovascular headaches’. Functional imaging findings suggest a possible role of the dorsolateral pons in generating migraine attacks while the role of the hypothalamus in cluster headache is more firmly established.
Conclusions: Migraine and cluster headache have complex pathophysiologies. The exact mechanism causing pain in both conditions is incompletely understood and more research needs to be undertaken in this area.

 
Keyword(s): MIGRAINE, CLUSTER HEADACHE, PAIN
 
 
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APA: Copy

BUTURE, A., & GOORIAH, R., & NIMERI, R., & AHMED, F. (2016). CURRENT UNDERSTANDING ON PAIN MECHANISM IN MIGRAINE AND CLUSTER HEADACHE. ANESTHESIOLOGY AND PAIN MEDICINE, 6(3), 0-0. https://www.sid.ir/en/journal/ViewPaper.aspx?id=509914



Vancouver: Copy

BUTURE ALINA, GOORIAH RUBESH, NIMERI RANDA, AHMED FAYYAZ. CURRENT UNDERSTANDING ON PAIN MECHANISM IN MIGRAINE AND CLUSTER HEADACHE. ANESTHESIOLOGY AND PAIN MEDICINE. 2016 [cited 2021July28];6(3):0-0. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509914



IEEE: Copy

BUTURE, A., GOORIAH, R., NIMERI, R., AHMED, F., 2016. CURRENT UNDERSTANDING ON PAIN MECHANISM IN MIGRAINE AND CLUSTER HEADACHE. ANESTHESIOLOGY AND PAIN MEDICINE, [online] 6(3), pp.0-0. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509914.



 
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