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Paper Information

Journal:   ANESTHESIOLOGY AND PAIN MEDICINE   JUNE 2016 , Volume 6 , Number 3; Page(s) 0 To 0.
 
Paper: 

THE ROLE OF CAFFEINE IN PAIN MANAGEMENT: A BRIEF LITERATURE REVIEW

 
 
Author(s):  BARATLOO ALIREZA, ROUHIPOUR ALALEH, FOROUZANFAR MOHAMMAD MEHDI, SAFARI SAEED, AMIRI MARZIEH, NEGIDA AHMED*
 
* STUDENT RESEARCH UNIT, ZAGAZIG UNIVERSITY, ZAGAZIG, EGYPT
 
Abstract: 

Context: Caffeine is the most commonly used psychoactive legal drug in the world. Caffeine’s role in controlling pain has received less attention in the past, yet is being increasingly considered. This article briefly reviewed the literature to clarify the role of caffeine as a drug for pain control and attract investigators to this topic.
Evidence Acquisition: The data on Caffeine as an adjuvant therapy or as a main component for pain modulation has been narratively reviewed.
Results: Caffeine plays an important role in pain modulation through their action on adenosine receptors which are involved in nociception. The use of caffeine as adjuvant treatment was well-established in the literature and caffeine is currently available in some over the counter medications. Studies showed controversial results about the interaction between caffeine and morphine for pain relief in patients with terminal stage cancer. As a main component for pain modulation, Caffeine can be used for hypnic headache and postdural puncture headache.
Conclusions: Caffeine has a potential role for pain modulation. Current evidence on caffeine use for migraine and terminal stage cancer is not well-established. Future studies should address the use of caffeine alone for different types of pain with dose escalation and standardization of outcome measurement.

 
Keyword(s): CAFFEINE, ADENOSINE, ROLE, PAIN MANAGEMENT
 
 
References: 
 
Citations: 
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APA: Copy

BARATLOO, A., & ROUHIPOUR, A., & FOROUZANFAR, M., & SAFARI, S., & AMIRI, M., & NEGIDA, A. (2016). THE ROLE OF CAFFEINE IN PAIN MANAGEMENT: A BRIEF LITERATURE REVIEW. ANESTHESIOLOGY AND PAIN MEDICINE, 6(3), 0-0. https://www.sid.ir/en/journal/ViewPaper.aspx?id=509875



Vancouver: Copy

BARATLOO ALIREZA, ROUHIPOUR ALALEH, FOROUZANFAR MOHAMMAD MEHDI, SAFARI SAEED, AMIRI MARZIEH, NEGIDA AHMED. THE ROLE OF CAFFEINE IN PAIN MANAGEMENT: A BRIEF LITERATURE REVIEW. ANESTHESIOLOGY AND PAIN MEDICINE. 2016 [cited 2021August04];6(3):0-0. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509875



IEEE: Copy

BARATLOO, A., ROUHIPOUR, A., FOROUZANFAR, M., SAFARI, S., AMIRI, M., NEGIDA, A., 2016. THE ROLE OF CAFFEINE IN PAIN MANAGEMENT: A BRIEF LITERATURE REVIEW. ANESTHESIOLOGY AND PAIN MEDICINE, [online] 6(3), pp.0-0. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509875.



 
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