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Paper Information

Journal:   GOVARESH JOURNAL   FALL 2015 , Volume 20 , Number SUPPLEMENT; Page(s) 28 To 28.
 
Paper: 

EFFECT OF DETERMINATION OF THE DIAGNOSTIC VALUE OF IGG AVIDITY TEST FOR CONFIRMATION OF ACUTE HELICOBACTER PYLORI INFECTION

 
 
Author(s):  POURI ALIASGHAR, SOMI MOHAMMAD HOSSEIN, SHIRMOHAMMADI MASOOD, BONYADI MOHAMMAD REZA, HAJAVI NASER*
 
* LIVER AND GASTROINTESTINAL DISEASES RESEARCH CENTER, TABRIZ UNIVERSITY OF MEDICAL SCIENCES, TABRIZ, IRAN
 
Abstract: 

Introduction: Infection with Helicobacter Pylori is common worldwide. Valid tests are available for diagnosis with pros and cons for each. This study evaluated diagnostic validity of Helicobacter IgG avidity test compared to stool testing to examine its efficiency for validating existence of an acute infection.
Methods: In this cross-sectional study, 50 patients referred to gastroenterology and Hepatology clinic of Imam Reza university hospital were selected and blood and stool samples were collected. Diagnostic validity of IgG avidity test was compared to results of stool testing by using Receiver Operating Characteristics (ROC) curves and the best cut-off value was calculated for avidity. Then sensitivity, specificity, positive and negative predictive values were calculated for this cut-off.
Results: The mean age of the patients was 31.12
± 7.7 years.31 patients (62.0%) were female and 19 (38.0%) were males. Serology was positive in 45 (90%) patients and stool testing was positive in 30 (60%). The Area under the Curve for IgG avidity was reported to be 0.753. The best cut-off was reported 82.5. in this level, sensitivity of IgG avidity was 80% and specificity was 74%. Again the positive predictive value is 75.5% and the negative predictive value is 78.7%.
Conclusion: Helicobacter Pylori IgG avidity which is independent from use of medications by the patients could be helpful in validating a negative stool AG testing.

 
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+ Click to Cite.
APA: Copy

POURI, A., & SOMI, M., & SHIRMOHAMMADI, M., & BONYADI, M., & HAJAVI, N. (2015). EFFECT OF DETERMINATION OF THE DIAGNOSTIC VALUE OF IGG AVIDITY TEST FOR CONFIRMATION OF ACUTE HELICOBACTER PYLORI INFECTION. GOVARESH JOURNAL, 20(SUPPLEMENT), 28-28. https://www.sid.ir/en/journal/ViewPaper.aspx?id=509764



Vancouver: Copy

POURI ALIASGHAR, SOMI MOHAMMAD HOSSEIN, SHIRMOHAMMADI MASOOD, BONYADI MOHAMMAD REZA, HAJAVI NASER. EFFECT OF DETERMINATION OF THE DIAGNOSTIC VALUE OF IGG AVIDITY TEST FOR CONFIRMATION OF ACUTE HELICOBACTER PYLORI INFECTION. GOVARESH JOURNAL. 2015 [cited 2021July28];20(SUPPLEMENT):28-28. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509764



IEEE: Copy

POURI, A., SOMI, M., SHIRMOHAMMADI, M., BONYADI, M., HAJAVI, N., 2015. EFFECT OF DETERMINATION OF THE DIAGNOSTIC VALUE OF IGG AVIDITY TEST FOR CONFIRMATION OF ACUTE HELICOBACTER PYLORI INFECTION. GOVARESH JOURNAL, [online] 20(SUPPLEMENT), pp.28-28. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509764.



 
 
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