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Paper Information

Journal:   GOVARESH JOURNAL   FALL 2015 , Volume 20 , Number SUPPLEMENT; Page(s) 26 To 27.
 
Paper: 

COMPARING THE ACCURACY OF HELICOBACTER PYLORI SEROLOGY DIAGNOSTIC TESTS IN CHILDREN WITH ENDOSCOPY AND UREA BREATH TEST

 
 
Author(s):  GHEIBI SHAHSANAM*, ESMAEILI GOUVARCHIN GHALEH HADI, KOUSEHLOU ZAHRA, MANSORI MOTLAGH BAHMAN
 
* URMIA UNIVERSITY OF MEDICAL SCIENCES
 
Abstract: 

Introduction: H. pylori causes peptic ulcer, gastric cancer and MALT lymphoma. Therefore, early detection and treatment of which is important. We assessed the accuracy of serologic test in the diagnosis of Helicobacter pylori with urea breath test and invasive rapid urease test.
Methods: This cross-sectional study was conducted on the 439 children 3-18 years old with dyspepsia and positive anti-Helicobacter pylori antibody without previous treatment for H. pylori infection. After obtaining written consent from their parents, rapid urease test (upper endoscopy) and urea breath test were considered as the gold standard tests for the diagnosis of H. pylori infection. Sensitivity, specificity, positive and negative predictive value of each anti-H.pylori (IgG, IgM) was examined.
Results: Of the 439 patients (195 male, 244 female) parents of 233 children chosen urea breath test and 208 children underwent upper endoscopy.95 children (40.8%) of 233 patients had positive urea breath test (more than 200 DPM) While 66 children (31.7%) of 208 patients had a positive rapid urease test.
Sensitivity and specificity of anti-Helicobacter pylori IgG with rapid urease test were 92/42 and 60/56 respectively, and 87.37 and 72.46 with the urea breathe test.
While the sensitivity and specificity of anti-Helicobacter pylori IgM with rapid urease test were 72/73 and 30.28 and 71.58 and 23.91with urea breathe test, respectively. Positive and negative predictive value of anti-Helicobacter pylori IgG with rapid urease test were 52.14 and 94.5, but with urea breath test were 68.59 and 89.28, respectively. Positive and negative predictive value of anti-Helicobacter pylori IgM with rapid urease test were 32.65 and 70.5 but with urea breath test were 39/31 and 55, respectively.
Conclusion: Urea breath test has over success than endoscopy in finding H. pylori infection in children.
IgG has greater value in screening for this infection.

 
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APA: Copy

GHEIBI, S., & ESMAEILI GOUVARCHIN GHALEH, H., & KOUSEHLOU, Z., & MANSORI MOTLAGH, B. (2015). COMPARING THE ACCURACY OF HELICOBACTER PYLORI SEROLOGY DIAGNOSTIC TESTS IN CHILDREN WITH ENDOSCOPY AND UREA BREATH TEST. GOVARESH JOURNAL, 20(SUPPLEMENT), 26-27. https://www.sid.ir/en/journal/ViewPaper.aspx?id=509752



Vancouver: Copy

GHEIBI SHAHSANAM, ESMAEILI GOUVARCHIN GHALEH HADI, KOUSEHLOU ZAHRA, MANSORI MOTLAGH BAHMAN. COMPARING THE ACCURACY OF HELICOBACTER PYLORI SEROLOGY DIAGNOSTIC TESTS IN CHILDREN WITH ENDOSCOPY AND UREA BREATH TEST. GOVARESH JOURNAL. 2015 [cited 2021July24];20(SUPPLEMENT):26-27. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509752



IEEE: Copy

GHEIBI, S., ESMAEILI GOUVARCHIN GHALEH, H., KOUSEHLOU, Z., MANSORI MOTLAGH, B., 2015. COMPARING THE ACCURACY OF HELICOBACTER PYLORI SEROLOGY DIAGNOSTIC TESTS IN CHILDREN WITH ENDOSCOPY AND UREA BREATH TEST. GOVARESH JOURNAL, [online] 20(SUPPLEMENT), pp.26-27. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509752.



 
 
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