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Paper Information

Journal:   GOVARESH JOURNAL   FALL 2015 , Volume 20 , Number SUPPLEMENT; Page(s) 21 To 21.
 
Paper: 

THE COMPARISON STUDY OF THE EFFECT OF ZINC SUPPLEMENTATION ON THE IMPROVEMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN PATIENTS ADMITTED IN ALIMENTARY CLINIC IN RASHT CITY

 
 
Author(s):  SHAFAGHI AFSHIN, MANSOUR GHANAEI FARIBORZ*, HASANZADEH JALAL, JUOKAR FARAHNAZ
 
* DEPARTMENT OF GASTROENTEROLOGY, GATSROINTESTINAL AND LIVER DISEASES RESEARCH CENTER (GLDRC), GUILAN UNIVERSITY OF MEDICAL SCIENCES, RASHT, IRAN
 
Abstract: 

Introduction: Gastroesophageal reflux disease one of the most common and most important of digestive system disorders which physicians are usually encountered. gastroesophageal reflux disease is dueto regurgitation of stomach contents that induces symptoms or damage to the tissue of the esophagus.
The purpose of this study, the comparison effect of zinc supplementation on the improvement of Gastroesophageal reflux symptoms in the incoming patients to gastroenterology clinic in Rasht city.
Methods: This study designed as a double blind clinical trial. The sampling type is easy or available.
The number of subjects studied was 140 patients who referred to the gastroenterology clinic, baseline FSSG standard questionnaire (12 items). Using this questionnaire, a score of 8 or more than 8, patients have been diagnosed with GERD. Patients undergoing upper gastrointestinal endoscopy were divided into two groups based on endoscopic were divided to (erosive reflux disease) and NERD (non erosive reflux disease, then Both groups with use of the random block, divided into experimental and control groups. In all cases, was given Nycomeb 20 mg and for experimental group 220 mg capsules of zinc and a placebo for the control group.
Results: In this study, the receiving group the drug were 48 females (68.6%) and 22 males (31.4%) in the receiving group placebo included, 33 patients female (47.1%) and 37 males (52.9%). Using Chi-Square test showed a significant difference between the drug and placebo groups in base of gender (P=0.05).
Conclusion: Our findings showed that zinc supplementation don’t have a considerably effect on the improvement reflux disease, as, only can be used as therapeutic plan in improvement and also frequency and severity diminish of some Gastroesophageal reflux symptoms.

 
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