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Paper Information

Journal:   GOVARESH JOURNAL   FALL 2015 , Volume 20 , Number SUPPLEMENT; Page(s) 15 To 15.
 
Paper: 

TRANSAMINE IN TREATMENT OF GI BLEEDING IN ICU PATIENTS

 
 
Author(s):  SARDARIAN HOSSEIN*
 
* BEHESHTI HOSPITAL, GUILAN
 
Abstract: 

Introduction: Gastrointestinal bleeding is common and it's mortality rate is about 10 percent, so strategies for decreasing this mortaliy specially in situation with limitation in endoscopic treatment of GI bleeding is very important. The transamine (tranexamic acid) is very important in treatment of bleeding conditions specially of oncologic, surgival and traumatic typs.
Therefor I decide to use transamine and IV pantozole in treatment of patient who admitted in ICU and endoscopic intervention is not possible.
Methods: IV transamine 1 gram stat and 1gram IV q6h plus transamine 1 gram in 1000CC noramal salin for NG tube irrigation plus pantozole 80 mg IV stat and 8mg/hr IV infusion was started. If bleeding contineud another 1 gram transamine for NG tube irrigation was prescribed. After 12-24 hours diagnostic endoscopic was done and efficacy of above treatment was evaluated.
Results: Transamine plus IV PPI was effective in contorole of GI bleeding in 95.6 percent (43/45) of patients admitted in ICU as a whole treatment. Only two patients was expired. Transamine was equally effective in male and female, all age ranges and in all types of GI bleeding.
Conclusion: So above treatment may be a effective treatment in patients with GI bleeng in situations with poor equipment and poor condition patients that endoscopic intervention was not possible.

 
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