Paper Information

Journal:   GOVARESH JOURNAL   FALL 2015 , Volume 20 , Number SUPPLEMENT; Page(s) 11 To 12.
 
Paper: 

EPIDEMIOLOGICAL EVALUATION OF NON ALCOHOLIC FATTY LIVER DISEASE AND RELATED FACTORS IN SANANDAJ CITY IN 2013-14: A POPULATION BASE STUDY

 
 
Author(s):  SHEIKHESMAEILI FARSHAD*, FATTAHI NIMA
 
* LIVER& DIGESTIVE RESERCH CENTER, KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, SANANDAJ, IRAN
 
Abstract: 

Introduction: Nonalcoholic fatty liver disease includes a range of liver diseases which start from simple fatty liver (hepatic steatosis) and can develop to hepatocellular carcinoma. Generally, 15% to 40% of the world's populations are suffering from NAFLD. The aim of this study was to conduct an epidemiological evaluation of non-alcoholic fatty liver disease and its risk factors in the city of Sanandaj.
Methods: This cross-sectional study was conducted from summer 2013 to summer 2014, for 12 months, in the city of Sanandaj. In this study, multistage cluster sampling method was used. Alcoholics, pregnant women, and patients with liver disease were excluded. The data about the subjects including their age, sex, body mass index, history of diabetes, hypertension, and heart disease were recorded. All the subjects underwent abdominal ultrasound; besides, patients with fatty liver underwent blood tests (cholesterol, AST, ALT, Alk.P, FBS, TG, Total HDL, LDL, HCVAb, HBSAg). Statistical analysiswas performed using descriptive statistics and logistic regression test.
Results: A total of 410 patients were included in the study, of whom 145 (35%) had nonalcoholic fatty liver disease. The prevalence of fatty liver in men (43%) was twice more than in women (22%). The highest prevalence rate was reported in the age group 50 to 60 years old. The severity of fatty liver disease was increased by raising blood sugar, triglycerides, and total cholesterol.
Conclusion: Based on the findings of this study, the prevalence of fatty liver disease in the general population of Sanandaj was equal with the highest rates reported from other countries and the prevalence was much higher than that in Asian countries. It is recommended to implement fast and effective interventions to control fatty liver disease.

 
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