Paper Information

Journal:   GOVARESH JOURNAL   FALL 2015 , Volume 20 , Number SUPPLEMENT; Page(s) 10 To 11.
 
Paper: 

EVALUATION OF HEPATITIS C INFECTION IN THE DRUG ABUSED PARTICIPANTS REFERRED TO SHIRAZ DRUG REHABILITATION CENTERS: A SERO-EPIDEMIOLOGIC EVALUATION

 
 
Author(s):  FATTAHI MOHAMMAD REZA, SEPEHRIMANESH MASOOD, SAFARPOUR ALI REZA, NEJABAT MARYAM, AFSHARI RAMIN*
 
* DEPUTY OF TREATMENT SHIRAZ UNIVERSITY OF MEDICAL SCIENCES, SHIRAZ, IRAN
 
Abstract: 

Introduction: Drug abuser is one of the most at risk population for HCV transmission worldwide.
The aims of this study were to measure the sero-prevalence of HCV and compare some related risk factors in participants who referred to drug rehabilitation centers affiliated to Shiraz University of Medical Sciences, Shiraz, Iran.
Methods: Blood samples and interviews contain questions about age, gender, education level, house status, jobs, history of imprisonment and psychiatry problems, age at first drug and first IV drug use, safe and unsafe sexual activity and time and duration of IV drug use in the past 30 days were obtained from 1043 participants in rehabilitation centers.
The sera were tested for anti-HCV antibody using enzyme immunoassay. The data were analyzed usingin dependent samples t test and one way ANOVA for quantitative variables and chi-square and Fisher’s exact tests for qualitative variables.
Results: Among 772 participants who agreed with blood sampling, the prevalence of HCV infection was 14.2%. The significant positive associations were detected between anti-HCV antibody positivity and some risk factors include higher education levels (P=0.015), no prison history (P<0.001), having a job (P=0.005), having a partner (P<0.001) and higher age at first drug (P<0.001).
Conclusion: The seroprevalence of HCV infection among drug abuser is very high in comparison with the general population of Iran. Performing the policies to prevent transmission of HCV infection among this high at risk sub-population is highly recommended.

 
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