Paper Information

Journal:   JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES   2015 , Volume 7 , Number 1; Page(s) 45 To 53.
 
Paper: 

PROGNOSTIC FACTORS IN THE SURVIVAL RATE OF COLORECTAL CANCER PATIENTS

 
DOI: 

10.29252/jnkums.7.1.45

 
Author(s):  PARSAEE R., FEKRI N., SHAHID SALES S., AFZAL AGHAEI M., SHAARBAF EIDGAHI E., ESMAEILY H.*
 
* HEALTH SCIENCES RESEARCH CENTER, DEPARTMENT OF BIOSTATISTICS AND EPIDEMIOLOGY, SCHOOL OF HEALTH, MASHHAD UNIVERSITY OF MEDICAL SCIENCES, MASHHAD, IRAN
 
Abstract: 

Background & objectives: colorectal cancer is The second common cancer in women and the third cancers in men. The aim of this study was to recognize of prognostic factors in the survival rate of colorectal cancer patients who referred to Omid Hospital of Mashhad from 2006 to 2011.
Material & Methods: In this historical cohort study, 241 colorectal cancer patients were investigated. Demographic and clinical data were collected. Then the prognostic factors were established by Cox model using SAS software. (
a=0.05).
Results: The mean age at diagnosis was 56.62±0.94 years. The 1, 2, 3, 4 years survival rate were 81%, 66%, 53% and 44% respectively and the Median survival time in five years period, was 3.348 years. In Cox regression model, recurrence, history of opioid consumption and Duke’s stage were determined as effective factors in the survival rate of patients. (P-value<0.05).
Conclusion: Considering different results from different studies, further studies to detection of Prognostic Factors in the survival rate of patients seem to be necessary.

 
Keyword(s): COLORECTAL CANCER, COX MODEL, KAPLAN-MEIER
 
References: 
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