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Paper Information

Journal:   GOVARESH JOURNAL   SPRING 2016 , Volume 21 , Number 1; Page(s) 76 To 80.
 
Paper: 

PRIMARY HEPATIC AMYLOIDOSIS WITH SEVERE CHOLESTASIS: A CASE REPORT

 
 
Author(s):  GHALAMKARI MARZIYE, KHATUNI MAHDI, TAHER MOHAMMAD*, KHANIKI MAHMOOD
 
* IMAM KHOMEINI HOSPITAL,TEHRAN UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Despite the fact that hepatic involvement is frequently seen in systemic primary amyloidosis, major hepatic symptoms as primary manifestation and severe impaired liver function are rare. Herein, we report a 38-year-old woman with primary hepatic amyloidosis, and severe portal hypertension. The patient had ascites and markedly elevated alkaline phosphatase level at presentation. She had a rapid downhill course resulting in death. In case of an unexplained intrahepatic cholestasis or portal hypertension the possibility of amyloidosis should be considered and a Congo red staining should be performed.

 
Keyword(s): INTRAHEPATIC CHOLESTASIS, PRIMARY AMYLOIDOSIS, LIVER AMYLOIDOSIS
 
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