Paper Information

Journal:   JOURNAL OF DIABETES AND METABOLIC DISORDERS   DECEMBER 2015-JANUARY 2016 , Volume 15 , Number 2; Page(s) 75 To 83.
 
Paper: 

EFFECT OF SEA URCHIN ECHINOMETRA MATHAEI EXTRACTION ON THE ?-AMYLASE ENZYME ACTIVITY

 
 
Author(s):  SOLEIMANI SOOLMAZ, MOEIN SOHEILA*, YOUSEFZADI MORTEZA, AMROLLAHI BIOKI NARGES
 
* EMAM HOSSEIN BLVD, HORMOZGAN UNIVERSITY OF MEDICAL SCIENCES, BANDAR ABBAS, POSTAL CODE:7919693116
 
Abstract: 

Background: sea urchins belonging to phylum echinoderms of marine invertebrates them found to possess excellent. Diabetes mellitus, metabolic diseases most prevalent in the world with a group of metabolic disorders characterized by different degrees is the first increase in blood glucose levels. The aim of the present research was undertaken to study the anti- diabetes activity of different extracts, coelomic fluid and pigments shells and spines of sea urchin of Echinodermata mathaei.
Methods: Isolation of different tissues extracts (spine, shell, gonad and aristotol lantern) sea urchin by three solvents (n- hexan, ethyl acetate, and methanol). Isolation coelomic fluid by buffered mode and pigments shell and spine by HCl of sea urchin anti-diabetes activity investigatedthrough inhibition
a-Amylase enzyme.
Results: According to the results of the study, coelomic fluid (CF), coelomocyte lysate and shell pigment of sea urchin highest activity in the anti-diabetes methods. Significant differences were observed at P<0.05.
Conclusion: The result of this research indicated that sea urchin of E. mathaei due to the high antioxidant activity, as well as, flavonoid compounds, have anti- diabetes activities too.

 
Keyword(s): α- AMYLASE ENZYME, DIABETES, ENZYME INHIBITION, SEA URCHIN, ECHINOMETRA MATHAEI
 
References: 
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