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Paper Information

Journal:   INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE   WINTER 2015 , Volume 4 , Number 1; Page(s) 1 To 8.
 
Paper: 

RAB11 IN DISEASE PROGRESSION (REVIEW ARTICLE)

 
 
Author(s):  BHUIN TANMAY, ROY JAGAT KUMAR*
 
* CYTOGENETICS LABORATORY, DEPARTMENT OF ZOOLOGY, BANARAS HINDU UNIVERSITY, VARANASI-221 005, INDIA
 
Abstract: 

Membrane/protein trafficking in the secretory/biosynthetic and endocytic pathways is mediated by vesicles. Vesicle trafficking in eukaryotes is regulated by a class of small monomeric GTPases: the Rab protein family. Rab proteins represent the largest branch of the Ras superfamily GTPases, and have been concerned in a variety of intracellular vesicle trafficking and different intracellular signalling pathways. Rab11 (a subfamily of the Ypt/Rab gene family), an evolutionarily conserved ubiquitously expressed subfamily of Rab GTPases, has been implicated in regulating vesicular trafficking through the recycling of endosomes. Rabs have been grouped into different subfamilies based on the distinct unambiguous sequence motifs. Three members: Rab11a, Rab11b and Rab25 make up the Rab11 GTPase subfamily. In this review article, we describe an overview over Rab11 subfamily with a brief structural aspect and its roles in implicating different disease progression.

 
Keyword(s): VESICLE TRAFFICKING, RAB PROTEINS, RAS SUPERFAMILY, RAB11, DISEASE PROGRESSION
 
 
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+ Click to Cite.
APA: Copy

BHUIN, T., & ROY, J. (2015). RAB11 IN DISEASE PROGRESSION (REVIEW ARTICLE). INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, 4(1), 1-8. https://www.sid.ir/en/journal/ViewPaper.aspx?id=509209



Vancouver: Copy

BHUIN TANMAY, ROY JAGAT KUMAR. RAB11 IN DISEASE PROGRESSION (REVIEW ARTICLE). INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE. 2015 [cited 2021May17];4(1):1-8. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509209



IEEE: Copy

BHUIN, T., ROY, J., 2015. RAB11 IN DISEASE PROGRESSION (REVIEW ARTICLE). INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, [online] 4(1), pp.1-8. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509209.



 
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