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Paper Information

Journal:   PAJOUHESH DAR PEZESHKI   2015 , Volume 39 , Number 4; Page(s) 163 To 168.
 
Paper: 

EFFECT OF REGULAR EXERCISE-INDUCED APELIN ON DYSLIPIDEMIA OF TYPE 2 DIABETIC RATS

 
 
Author(s):  KAZEMI FAHIMEH*, EBRAHIM KHOSROO, ZAHEDI ASL SALEH
 
* SCHOOL OF PHYSICAL EDUCATION AND SPORT SCIENCES, SHAHID BEHESHTI UNIVERSITY
 
Abstract: 

Background: Recently the role of apelin in improvement of dislipidemia has been known. The purpose of this study was to determine the effect of regular exercise-induced apelin on dyslipidemia of type 2 diabetic rats.
Methods: Twenty eight diabetic male Wistar rats were divided into 3 groups: Non-diabetic (n=9), control diabetic (n=9) and trained diabetic (n=10). Type 2 diabetes was induced by injection of nicotinamide and streptozotocin. The aerobic training program included 8-week running on treadmill progressively for 45 min at a speed of 24 m/min and a 5% grade. After the period of training, plasma level of apelin and lipids (TC, HDL-C, LDL-C, VLDL-C, TG and FFA) were measured. One-way analysis of variance (ANOVA) was used for analyzing data and p<0.05 was considered to be statistically significant.
Results: In trained diabetic compared with control diabetic group, a significant increase in apelin, a significant decrease in plasma level of LDL-C, VLDL-C and TG, an insignificant decrease in TC and FFA, and an insignificant increase in HDL-C were observed.
Conclusion: Results of present study showed that increase in plasma level of apelin following regular exercise by inhibition of lipolysis and decrease of blood lipids can improve dyslipidemia of type 2 diabetic rats.

 
Keyword(s): APELIN, DIABETES, HYPERLIPIDEMIA, AEROBIC EXERCISE
 
 
References: 
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Click to Cite.
APA: Copy

KAZEMI, F., & EBRAHIM, K., & ZAHEDI ASL, S. (2015). EFFECT OF REGULAR EXERCISE-INDUCED APELIN ON DYSLIPIDEMIA OF TYPE 2 DIABETIC RATS. PAJOUHESH DAR PEZESHKI, 39(4), 163-168. https://www.sid.ir/en/journal/ViewPaper.aspx?id=509111



Vancouver: Copy

KAZEMI FAHIMEH, EBRAHIM KHOSROO, ZAHEDI ASL SALEH. EFFECT OF REGULAR EXERCISE-INDUCED APELIN ON DYSLIPIDEMIA OF TYPE 2 DIABETIC RATS. PAJOUHESH DAR PEZESHKI. 2015 [cited 2021May07];39(4):163-168. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509111



IEEE: Copy

KAZEMI, F., EBRAHIM, K., ZAHEDI ASL, S., 2015. EFFECT OF REGULAR EXERCISE-INDUCED APELIN ON DYSLIPIDEMIA OF TYPE 2 DIABETIC RATS. PAJOUHESH DAR PEZESHKI, [online] 39(4), pp.163-168. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=509111.



 
 
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