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Paper Information

Journal:   IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS   January-February 2016 , Volume 31 , Number 6 (74); Page(s) 1005 To 1112.
 
Paper: 

EFFECTS OF CEYLON CINNAMON ETHANOLIC EXTRACT AND FLAXSEED OIL ON CUTANEOUS WOUNDS HEALING IN RAT

 
 
Author(s):  HESARAKI S., FARAHPOUR M.R., YAHYAEI B.*
 
* DEPARTMENT OF MEDICAL SCIENCES, ISLAMIC AZAD UNIVERSITY, SHAHROOD BRANCH, SHAHROOD, IRAN
 
Abstract: 

Wound is an inevitable event in life, occurring due to microbial infection or physical or chemical damage. The present study was conducted in order to compare the effect of Ceylon cinnamon extract and flaxseed oil on the healing of wounds induced in rat. Thirty-two rats were divided into four groups. The wound healing process was evaluated for groups related to Ceylon cinnamon ethanolic extract (3%) and flaxseed oil at a concentration of 3% on days 3, 7, 14 and 21. In addition, one group received no treatment as control, and one group received the Vaseline eucerin ointment as reference standard. The results showed that Ceylon cinnamon extract and flaxseed oil were effective in accelerating the wounds healing process and, in particular, increased epithelization rate in the treatment groups compared to the other groups, so that the size of the wound area in the Ceylon cinnamon group, flaxseed oil group, placebo group and the control group on day 21 were calculated to be 2.6±0.4, 3.72±0.05, 5.01±0.09 and 5.3±0.07, respectively. Comparative evaluation of this study showed that Ceylon cinnamon was more effective in accelerating the closure of wound as compared with flaxseed oil.

 
Keyword(s): WOUND HEALING, CEYLON CINNAMON, FLAXSEED OIL, EPITHELIZATION
 
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