Dear Editor: Postpartum blues, as a transient phenomenon of mood changes, generally begins 1 to 3 days after the child birth. This phenomenon is accompanied with symptoms such as unstable moods, ranging from euphoria to sadness, high sensitivity, crying for no reason, restlessness, poor concentration, anxiety, irritability, and anger. Prevalence of postpartum blues has been estimated 44.3% in Hong- Kong, 31.3% in Nigeria, 2 and 58% in India. In Iran, 22.3% of women suffer from weak postpartum blues, 10.8% have medium, and 21.1% suffer from severe postpartum blues. Interaction between different biological, psychological and social factors could affect the postpartum blues.