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Paper Information

Journal:   RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)   JANUARY-FEBRUARY 2016 , Volume 22 , Number 140; Page(s) 43 To 54.
 
Paper: 

POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS

 
 
Author(s):  MOOSSAVI ABDOLLAH, FARAJI LEILA
 
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Abstract: 

Background: Tinnitus is a specific auditory sensitivity in which the patient hears nonexistent sounds. From neurological point of view, in majority of them increment in neural activity has been characterized by increase in spontaneous firing rate in central auditory system.
According to a hypothesis, tinnitus is a result of abnormal synaptic plasticity and reduced inhibitory amino acidic NTM in auditory neural network. This compensatory reduction of inhibition to partial differentiation (due to hearing pathologies, acoustic trauma, …) results in elevated neural firing rate and hyperactivity mainly in fusiform cells in DCN. In this review article was Effort survey effect of DCN synaptic plasticity and tinnitus.
Methods: At this review article, some articles about synaptic plasticity and tinnitus in DCN from Google scholar, PubMed and Scopus and Science Direct were searched from 1988 to 2013 and reviewed accordingly.
Results: DCN is the lowest level of auditory system and synaptic plasticity and hyperactivity after hearing impairment occur there. This event increases the tendency to tinnitus. Though, this does not mean other auditory centers have no effect in tinnitus.

 
Keyword(s): TINNITUS, SYNAPTIC PLASTICITY, DORSAL COCHLEAR NUCLEUS (DCN)
 
 
References: 
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Click to Cite.
APA: Copy

MOOSSAVI, A., & FARAJI, L. (2016). POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 22(140), 43-54. https://www.sid.ir/en/journal/ViewPaper.aspx?id=508612



Vancouver: Copy

MOOSSAVI ABDOLLAH, FARAJI LEILA. POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES). 2016 [cited 2021May14];22(140):43-54. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=508612



IEEE: Copy

MOOSSAVI, A., FARAJI, L., 2016. POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), [online] 22(140), pp.43-54. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=508612.



 
 
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