Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES   MARCH-APRIL 2016 , Volume 23 , Number 1; Page(s) 14 To 20.
 
Paper: 

COMPARISON OF EFFECT OF PROMETHAZINE AND DICLOFENAC ON PAIN CONTROL OF APPENDECTOMY SURGERY: A RANDOMIZED CLINICAL TRIAL

 
 
Author(s):  TADAYON FAR MUSA AL REZA, AMADANI MEHDI, TAJABADI ALI, TABARAYI YASSER, KHOSROWGERDI HOSSEIN*
 
* SHAHID BEHESHTI HOSPITAL, SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, SABZEVAR, IRAN
 
Abstract: 

Background & Objectives: Pain after surgery, especially in appendectomy, is one of the most common causes of patients’ dissatisfaction. Regarding common side effects of existing analgesics, the researchers decided to replace conventional medicine for overcoming postoperative pain in such patients. Therefore, the aim of this study is to compare the pain relief effects of diclofenac and promethazine in patients with appendectomy.
Materials & Methodes: This triple blind clinical trial was performed on 60 patients of 49 -15 years old undergoing appendectomy in Shahid Doctor Beheshti Hospital of Sabzevar in 2012. Participants were selected by convenience sampling and randomly divided into two 30-cases groups of control and intervention, respectively received diclofenac promethazine by muscle depth injection in Dursuglutyal muscle. According to the standard numeric pain scale, the pain was investigated in the first hours after treatment. Data were analyzed using the Pearson chi-square test and SPSS version 18, and the level of significance was selected as 0.05.
Results: The difference of postoperative pain relief was significant (P=0.018) between the two groups at a half an hour. The average amount of pain in half an hour after injection of diclofenac and promethazine were 5.04±2.26 and 3.96±1.33, respectively. Also, the average amount of pain in one hour after injection of diclofenac and promethazine were 4.59±5.31 and 3.30±1.33, respectively. However, the differences were not statistically significant (P=0.177).
Conclusion: Promethazine is of greater analgesic efficacy than diclofenac. Therefore, a basic planing is recommended for the use of phenothiazines instead of highly morbid analgesics like non -steroidal anti-inflammatory drugs.

 
Keyword(s): PAIN, PROMETHAZINE, DICLOFENAC, ANALGESIC, APPENDECTOMY
 
 
References: 
  • Not Registered.
  •  
 
+ Click to Cite.
APA: Copy

TADAYON FAR, M., & AMADANI, M., & TAJABADI, A., & TABARAYI, Y., & KHOSROWGERDI, H. (2016). COMPARISON OF EFFECT OF PROMETHAZINE AND DICLOFENAC ON PAIN CONTROL OF APPENDECTOMY SURGERY: A RANDOMIZED CLINICAL TRIAL. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 23(1), 14-20. https://www.sid.ir/en/journal/ViewPaper.aspx?id=508504



Vancouver: Copy

TADAYON FAR MUSA AL REZA, AMADANI MEHDI, TAJABADI ALI, TABARAYI YASSER, KHOSROWGERDI HOSSEIN. COMPARISON OF EFFECT OF PROMETHAZINE AND DICLOFENAC ON PAIN CONTROL OF APPENDECTOMY SURGERY: A RANDOMIZED CLINICAL TRIAL. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES. 2016 [cited 2021May16];23(1):14-20. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=508504



IEEE: Copy

TADAYON FAR, M., AMADANI, M., TAJABADI, A., TABARAYI, Y., KHOSROWGERDI, H., 2016. COMPARISON OF EFFECT OF PROMETHAZINE AND DICLOFENAC ON PAIN CONTROL OF APPENDECTOMY SURGERY: A RANDOMIZED CLINICAL TRIAL. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, [online] 23(1), pp.14-20. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=508504.



 
 
Persian Abstract Yearly Visit 97
 
Latest on Blog
Enter SID Blog