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Paper Information

Journal:   JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY   2015 , Volume - , Number 70; Page(s) 37 To 44.
 
Paper: 

THEORETICAL AND EXPERIMENTAL STUDIES OF 161TB PRODUCTION AS A NEW THERAPEUTIC RADIONUCLIDE AT TEHRAN RESEARCH REACTOR

 
 
Author(s):  SHARIFI M., YOUSEFNIA H., BAHRAMI SAMANI A., JALILIAN A.R., ZOLGHADRI S.*, GHANNADI MARAGHEH M.
 
* NUCLEAR FUEL CYCLE RESEARCH SCHOOL, NUCLEAR SCIENCE AND TECHNOLOGY RESEARCH INSTITUTE, AEOI, TEHRAN – IRAN
 
Abstract: 

Because of the suitable decay characteristics of terbium-161 (161Tb), it is a promising radioisotope for development of new therapeutic complexes and also a good alternative to 177Lu. In this study, the production routes of 161Tb are evaluated by both theoretical and experimental methods. In the theoretical approach the chain decay equations are solved and the activity of the radionuclide and all of the other products are obtained by imposing constant values in the equations. The main route for the 161Tb production is the 160Gd (n, ?)161Gd (b-)161Tb reaction as an indirect production method. In this method, natural or enriched gadolinium can be used. For the 161Tb production, 1 mg of natural gadolinium is irradiated at the Tehran Research Reactor, using thermal neutron flux of 3×1013 cm-2 s-1 for 34 hours. The activity of each product is evaluated by means of gamma spectrometry. The results show that about 0.11 mCi of 161Tb is produced in this condition. Due to confirmation of the calculations with experiments, it can be concluded that production of about 100 mCi of 161Tb is possible by a long time irradiation of 10 mg of enriched 160Gd.

 
Keyword(s): TERBIUM-161, GADOLINIUM, THERAPEUTIC RADIONUCLIDE, TEHRAN RESEARCH REACTOR
 
 
References: 
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Click to Cite.
APA: Copy

SHARIFI, M., & YOUSEFNIA, H., & BAHRAMI SAMANI, A., & JALILIAN, A., & ZOLGHADRI, S., & GHANNADI MARAGHEH, M. (2015). THEORETICAL AND EXPERIMENTAL STUDIES OF 161TB PRODUCTION AS A NEW THERAPEUTIC RADIONUCLIDE AT TEHRAN RESEARCH REACTOR. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, -(70), 37-44. https://www.sid.ir/en/journal/ViewPaper.aspx?id=508447



Vancouver: Copy

SHARIFI M., YOUSEFNIA H., BAHRAMI SAMANI A., JALILIAN A.R., ZOLGHADRI S., GHANNADI MARAGHEH M.. THEORETICAL AND EXPERIMENTAL STUDIES OF 161TB PRODUCTION AS A NEW THERAPEUTIC RADIONUCLIDE AT TEHRAN RESEARCH REACTOR. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY. 2015 [cited 2021May10];-(70):37-44. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=508447



IEEE: Copy

SHARIFI, M., YOUSEFNIA, H., BAHRAMI SAMANI, A., JALILIAN, A., ZOLGHADRI, S., GHANNADI MARAGHEH, M., 2015. THEORETICAL AND EXPERIMENTAL STUDIES OF 161TB PRODUCTION AS A NEW THERAPEUTIC RADIONUCLIDE AT TEHRAN RESEARCH REACTOR. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, [online] -(70), pp.37-44. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=508447.



 
 
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