The input-oriented Data Envelopment Analysis was used to measure the water use efficiency and productivity indices of Tehran over the period 2005-13. Meanwhile, the correlation between water uses and regional economic activities was examined using the gross regional domestic product index. The results indicated that the total productivity was improved 1.8% and 1.68% aspect of technical efficiency change and scale efficiency change respectively. Furthermore, it was improved 12.32% aspect of technology change due to accumulation and treatment of wastewater and applying water use management to increase annual water storage since 2011. The mentioned indices confirmed that a 22 million cubic meters decrease is possible in water uses without decreasing in the level of gross products related to Tehran.