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Paper Information

Journal:   JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH   DECEMBER 2014 , Volume 8 , Number 4; Page(s) 189 To 193.
 
Paper: 

CONSANGUINITY AND NEONATAL DEATH: A NESTED CASE-CONTROL STUDY

 
 
Author(s):  CHAMAN REZA*, GHOLAMI TARAMSARI MAHSHID, KHOSRAVI AHMAD, AMIRI MOHAMMAD, HOLAKOUIE NAIENI KOUROSH, YUNESIAN MASOUD
 
* DEPARTMENT OF COMMUNITY MEDICINE, SCHOOL OF MEDICINE, YASUJUNIVERSITY OF MEDICAL SCIENCES, YASUJ, IRAN
 
Abstract: 

Objective: Although numerous studies have found higher rates of abortion and still births following consanguinity (familial marriages), the question of whether consanguinity significantly increases the risk of neonatal death has inadequately been addressed.This study aims to evaluate familial marriage effects on neonatal death in rural areas in Iran.
Materials and methods: In this nested case-control study, 6900 newbornswho were born in rural areas of Kohgiluyeh and Boyerahmad Province (South-West of Iran) were followed till the end of neonatal period, and neonatal death was the outcome of interest. Subsequently 97 cases and 97 controls were selected in study cohort by using risk set sampling model. Crude and adjusted odds ratios (OR) were estimated by usinga conditional logistic regression model.
Results: In the final model, prematurity (OR=5.57), low birthweight (LBW) (OR=7.68), consanguinity (first cousins) (OR=5.23), C-section (OR=7.27), birth rank more than 3 (OR=6.95) and birthsinterval less than 24 months (OR=4.65) showed significant statistical association with neonatal mortality (p<0.05).
Conclusion: According to our findings, after adjusting the effects of other significant risk factors, familial marriageto first cousins is considered asan important risk factor for neonatal death.

 
Keyword(s): NEONATAL DEATH, NESTED CASE- CONTROL STUDY, CONSANGUINITY, RURAL AREAS, IRAN
 
 
References: 
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Click to Cite.
APA: Copy

CHAMAN, R., & GHOLAMI TARAMSARI, M., & KHOSRAVI, A., & AMIRI, M., & HOLAKOUIE NAIENI, K., & YUNESIAN, M. (2014). CONSANGUINITY AND NEONATAL DEATH: A NESTED CASE-CONTROL STUDY. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH, 8(4), 189-193. https://www.sid.ir/en/journal/ViewPaper.aspx?id=508248



Vancouver: Copy

CHAMAN REZA, GHOLAMI TARAMSARI MAHSHID, KHOSRAVI AHMAD, AMIRI MOHAMMAD, HOLAKOUIE NAIENI KOUROSH, YUNESIAN MASOUD. CONSANGUINITY AND NEONATAL DEATH: A NESTED CASE-CONTROL STUDY. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH. 2014 [cited 2021May11];8(4):189-193. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=508248



IEEE: Copy

CHAMAN, R., GHOLAMI TARAMSARI, M., KHOSRAVI, A., AMIRI, M., HOLAKOUIE NAIENI, K., YUNESIAN, M., 2014. CONSANGUINITY AND NEONATAL DEATH: A NESTED CASE-CONTROL STUDY. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH, [online] 8(4), pp.189-193. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=508248.



 
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