Paper Information

Journal:   JOURNAL OF ORAL HEALTH AND ORAL EPIDEMIOLOGY   2016 , Volume 5 , Number 2; Page(s) 0 To 0.
 
Paper: 

ORAL LEUKOPLAKIA: DIAGNOSIS AND TREATMENT (REVIEW ARTICLE)

 
 
Author(s):  KJAERGAARD LARSEN MARIE*, SORENSEN JENS AHM, GODBALLE CHRISTIAN, THYGESEN TORBEN HENRIK
 
* DEPARTMENT OF ORAL AND MAXILLOFACIAL SURGERY, ODENSE UNIVERSITY HOSPITAL, ODENSE, DENMARK
 
Abstract: 

BACKGROUND AND AIM: Oral leukoplakia (OL) is a common premalignant lesion. The possible benefits of specific interventions in preventing a malignant transformation of OL are not well understood. This review assesses different invasive treatment techniques for OL and evaluate the optimal treatment possibilities.
METHODS: A Medline (PubMed) search was conducted and heterogeneity between the studies was found, e.g., with regard to the OL lesions, patient groups, follow-up time, and definition of recurrence.
RESULTS: The recurrence and malignant transformation rate after the different treatment methods were evaluated. The mean overall recurrence rate varied with the treatment method.
CONCLUSION: A surgical treatment appears to decrease the risk of transformation but does not fully eliminate it. Follow-up should be done regardless of the surgical treatment.

 
Keyword(s): ORAL LEUKOPLAKIA, SQUAMOUS CELL CARCINOMA, CHEMOTHERAPY, LASER ABLATION, CRYOSURGERY
 
References: 
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