Paper Information

Journal:   IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR)   2016 , Volume 17 , Number 1 (54); Page(s) 50 To 54.
 
Paper: 

SHORT PAPER: IMMUNOHISTOCHEMICAL EXPRESSION OF GHRELIN IN CAPSAICIN-TREATED RAT OVARIES DURING THE DIFFERENT DEVELOPMENTAL PERIODS

 
 
Author(s):  TUTUNCU S.*, ILHAN T., OZFILIZ N.
 
* DEPARTMENT OF HISTOLOGY AND EMBRYOLOGY, FACULTY OF VETERINARY MEDICINE, ONDOKUZ MAYIS UNIVERSITY, SAMSUN, TURKEY
 
Abstract: 

Red hot pepper is a plant that belongs to the Solanaceae family and is known asCapsicum annuum. Capsaicin is the active ingredient of cayenne pepper. Ghrelin is a hormone, which consists of polypeptide structure. Ghrelin also contributes to growth hormone secretion, energy balance, food intake and body weight regulator. The aim of this study was the localization and expression of ghrelin in the ovaries of rats treated with capsaicin during the postnatal development. Ninety female Sprague-Dawley rats (21 d) were used. The rats were randomly divided into 3 groups (n=30 each) as pubertal, post pubertal and adult. Each group was subdivided into three groups. The first subgroup (control) was given no injections. The second subgroup (vehicle) received only 0.3 cc solvent and the third subgroup (experiment) received subcutaneous injection of equal volume of capsaicin (1 mg/kg/d) for 42, 56, and 70 days. Ghrelin immunoreactivity was determined in ovarian follicular granulosa cells, interstitial cells and corpus luteal cells. A ghrelin immunopositive reaction located in the cytoplasm of cells in all groups. These results indicate that prolonged administration of low dose capsaicin does not affect ghrelin expression. However, follicular atresia was seen in lower rate in capsaicin treated group in comparison to other groups.

 
Keyword(s): CAPSAICIN, GHRELIN, IMMUNOHISTOCHEMISTRY, OVARY, RAT
 
References: 
  • ندارد
 
  pdf-File tarjomyar Yearly Visit 73
 
Latest on Blog
Enter SID Blog