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Paper Information

Journal:   JOURNAL OF RESEARCH IN HEALTH SCIENCES (JRHS)   2016 , Volume 16 , Number 2; Page(s) 68 To 71.
 
Paper: 

HELICOBACTER PYLORI INFECTION IN CHILDREN WITH TYPE 1 DIABETES MELLITUS: A CASE-CONTROL STUDY

 
 
Author(s):  BAZMAMOUN HASSAN, RAFEEY MANDANA, NIKPOURI MARYAM, GHERGHEREHCHI ROBABEH*
 
* DEPARTMENT OF PEDIATRIC, SCHOOL OF MEDICINE, TABRIZ UNIVERSITY OF MEDICAL SCIENCES, TABRIZ, IRAN
 
Abstract: 

Background: Helicobacter pylori infection is one of the most common chronic bacterial infections. There is challenge on the real rate of prevalence of H. pylori in diabetic patients. This study was done to assess the prevalence of H. pylori infection in children suffering from type 1 insulin-dependent diabetes mellitus.
Methods: In this case-control study, 80 diabetic patients (as the target group) refer to the Endocrinology Clinic of Tabriz Educational and Treatment Center, Tabriz northwestern Iran and 80 non-diabetic patients (as the control group) from the group of children referring to the GI Clinic of the same center were enrolled in 2012 and 2013. Then H. pylori infection was assessed in two groups using measuring antibody (IgG) and stool antigen (HpSA).
Results: H. pylori infection tests were positive in 48 (60%) diabetic patients and in 32 (40%) in non-diabetic patients (P=0.030). There was a meaningful correlation between the frequency of H. pylori and the longer the duration of diabetes (P<0.001). No correlation was seen between H. pylori infection and other factors such as age of the patients (P=0.840), HbA1C level (P=0.312), age at which diabetes was diagnosed (P=0.800), average daily dosage of insulin (P=0.232), and presence of GI symptoms (P=0.430).
Conclusions: Type 1 diabetic children especially cases with the longer duration of diabetes, are at risk acquiring H. pylori infection. Therefore, screening of H. pylori infection is helpful on the follow up of these patients.

 
Keyword(s): HELICOBACTER PYLORI, DIABETES MELLITUS, INSULIN-DEPENDENT, CHILDREN
 
 
References: 
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Click to Cite.
APA: Copy

BAZMAMOUN, H., & RAFEEY, M., & NIKPOURI, M., & GHERGHEREHCHI, R. (2016). HELICOBACTER PYLORI INFECTION IN CHILDREN WITH TYPE 1 DIABETES MELLITUS: A CASE-CONTROL STUDY. JOURNAL OF RESEARCH IN HEALTH SCIENCES (JRHS), 16(2), 68-71. https://www.sid.ir/en/journal/ViewPaper.aspx?id=507820



Vancouver: Copy

BAZMAMOUN HASSAN, RAFEEY MANDANA, NIKPOURI MARYAM, GHERGHEREHCHI ROBABEH. HELICOBACTER PYLORI INFECTION IN CHILDREN WITH TYPE 1 DIABETES MELLITUS: A CASE-CONTROL STUDY. JOURNAL OF RESEARCH IN HEALTH SCIENCES (JRHS). 2016 [cited 2021May07];16(2):68-71. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=507820



IEEE: Copy

BAZMAMOUN, H., RAFEEY, M., NIKPOURI, M., GHERGHEREHCHI, R., 2016. HELICOBACTER PYLORI INFECTION IN CHILDREN WITH TYPE 1 DIABETES MELLITUS: A CASE-CONTROL STUDY. JOURNAL OF RESEARCH IN HEALTH SCIENCES (JRHS), [online] 16(2), pp.68-71. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=507820.



 
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