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Paper Information

Journal:   JOURNAL OF NURSE AND PHYSICIAN WITHIN WAR   SUMMER 2015 , Volume 3 , Number 7; Page(s) 33 To 37.
 
Paper: 

EVALUATION OF ANTIBACTERIAL EFFECT OF ZATARIA MULTIFLORA ALCOHOLIC EXTRACT ON EXTENDED-SPECTRUM BETA-LACTAMASE (ESBL) PRODUCING STRAINS OF E.COLI ISOLATED FROM URINARY TRACT INFECTIONS IN THE IMAM REZA HOSPITAL

 
 
Author(s):  FARAHNEJAD Z., NAJAFI FARD M., DORMANESH B., NOJOOMI F.*
 
* DEPARTMENT OF MICROBIOLOGY, FACULTY OF MEDICINE, AJA UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Introduction: Escherichia coli (E. coli), is the most common bacteria that cause urinary tract infections in women. Nowaday, many strains of E.coli have been resistant to beta-lactam antibiotics and bacterial Beta-lactamases, have an important role. The aim of this study was to investigate the role of thyme alcoholic extract on Extended-spectrum betalactamase (ESBL) producing strains of E.coli.
Methods: After preparing the alcoholic extract of Zataria multiflora, concentrations 200, 100, 50, 25 and 400
mg/ml of this extract on ESBL-producing isolates of E.Coli was investigated, by agar disk diffusion method.
Results: The results showed that the inhibitory effect of Zataria multiflora alcoholic extract on the growth of ESBL-producing strains of E. coli in concentrations 100 and 400
mg /ml, was significantly increased. (P<0.05).
Conclusion: Based on this study results, the alcoholic extract of Zataria multiflora has considerable inhibitory effects on ESBLproducing E. coli strains, in vitro.

 
Keyword(s): ZATARIA MULTIFLORA, ESCHERICHIA COLI, ESBL, URINARY TRACT INFECTION
 
References: 
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