Paper Information

Journal:   NANOMEDICINE JOURNAL   SUMMER 2016 , Volume 3 , Number 3; Page(s) 191 To 195.
 
Paper: 

ANTIBACTERIAL EFFECT ASSESSMENT OF ZNS: AG NANOPARTICLES

 
 
Author(s):  PARVIN NAJME, AMIRI GHOLAMREZA*, KARBASIZADE VAJIHE
 
* FALAVARJAN BRANCH, ISLAMIC AZAD UNIVERSITY, ISFAHAN, IRAN
 
Abstract: 

Objective(s): A large ratio of surface to volume of nanoparticles in comparison with bulk ones, will increase the cell penetration and therefore their toxicity.
Materials and Methods: Chemical precipitation method was used in order to synthesis of ZnS:Ag quantum dots. Their Physical properties and characteristics were assessed by X-ray diffraction, Ultra Violet-Visible Spectrophotometer, Transmission Electron Microscope and it was shown that the obtained ZnS:Ag quantum dots are cubic with highquality. Antibacterial effects of ZnS:Ag nanoparticles against Pseudomonas aeroginosa, Staphylococcus aureus and Salmonella typhi were investigated. Disc bacteriological tests were used in order to assessment of the antibacterial effects of ZnS:Ag nanoparticles.
Results: The size of inhibition zone was different according to the type of bacteria and the concentrations of ZnS:Ag QDs. The maximum diameter was happened for S. aureus. The results of MICs obtained fromBroth Dilution for Pseudomonas aeruginosa, Staphylococcus aureus and Salmonella typhi, are 3.05, 3.05 and 6.1 mg/ml whereas the amounts of obtained MBCs are 12.2, 6.1 and 12.2 mg/ml respectively.
Conclusion: In conclusion, by increasing the nanoparticle concentration in wells and discs, the growth inhibition and diameter of inhibition zone has also been increased.

 
Keyword(s): ANTIBACTERIAL EFFECT, PSEUDOMONAS AERUGINOSA, QUANTUM DOTS, STAPHYLOCOCCI AUREUS, SALMONELLA TYPHI
 
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