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Paper Information

Journal:   AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)   Spring 2003 , Volume 10 , Number 1; Page(s) 30 To 34.
 
Paper: 

HISTOMORPHOMETRY OF TRABECULAR BONE OF CAUDAL VERTEBRAE DURING RAT PREGNANCY

 
 
Author(s):  SHAHTAHERI SM.*
 
* Department of Histology, School of Medicine, Hamadan University of Medical Sciences & Health Services, Hamadan, Iran
 
Abstract: 

Pregnancy make demands upon maternal calcium homeostasis and the extent to which the maternal bone mass is effected remains uncertain. Recently changes in the bone mass during human pregnancy have been associated also with the transformation of the cancellous architecture and the bone surface available for exchange. These jistomorphometrical structural changes were examined further in an animal, model. Using uniparous laboratory rats fed libitum, the histomorphometry of cancellous bone was compared in undecalcified of caudal vertebrae. Between 3 and 6 sections (8 pm) were analyzed by an automated trabecular analysis system (TAS) which measures a comprehensive range of structural variables including the trabecular separation, number, connectivity and width. There was an early stimulation of bone formation that was indicated by generation of thicker and interconnected trabecular. However in caudal vertebrae, there were architectural changes in cancellous bone commencing with a significant increase in the trabecular separation. It was concluded that strengthens the cancellous component of the maternal skeleton possibly to counter increased load and to facilitate mineral mobilization in maternal/neonate exchange during the subsequent lactation period‏.‏

 
Keyword(s): BONE HISTOMORPHOMETRY, CALCIUM HEMEOSTASIS, PREGNANCY, RATS
 
References: 
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