Paper Information

Journal:   JOURNAL OF DENTAL MEDICINE   2003 , Volume 16 , Number 2 (35); Page(s) 79 To 84.
 
Paper: 

A CASE REPORT ON A SYSTEMIC TOXICITY FOLLOWING INGESTION OF 20% CHLORHEXIDINE GLUCONATE SOLUTION

 
 
Author(s):  KOLAHI-E-KAZERANI J., GHALYANI ESFAHANI P., VARSHOUSAZ J.
 
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Abstract: 

The health of habitants, living in un-fluoridated drinking water areas, can be endangered through fluoride intake from food, beverages, toothpaste and dentistry products. Fluoride is used in mouthwash, toothpaste, juice fruits, conserved foods and Teflon dishes. Water exposure to fluoride occurs through fertilizers, aluminum industries, insecticides, pesticides, herbicides and fungicides used for fruits and vegetables, which ultimately lead to environmental fluoride pollution. Some side effects, caused by chronic fluoride intake are as follows: decrease of hemoglobin concentration, gastrointestinal disorders, and tooth loss at young age, osteofluorosis, hip fracture among aged people, osteosclerosis, osteoporosis, special forms of arthritis and joint ankylosis, metaphysial osteomalacia, mottling and weak structure of tooth, insulin secretion and glucose tolerance test disorders, decrease of urine concentration, immune system disorders, genetic defects and cancer, learning disabilities and IQ(intelligence quotient) deficits and thyroid dysfunction, … . The present article was to investigate the side effect of excessive fluoride intake and to discuss different preventive and diagnostic ways.

 
Keyword(s): CHLORHEXIDINE GLUCONATE, SYSTEMIC TOXICITY, LIVER NECROSIS, BISBIGUANIDES
 
References: 
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