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Paper Information

Journal:   ARCHIVES OF IRANIAN MEDICINE   NOVEMBER 2014 , Volume 17 , Number 11; Page(s) 779 To 782.
 
Paper: 

MASSIVE HEMOPTYSIS: A RARE PRESENTATION OF POSTERIOR MEDIASTINAL, GIANT, BENIGN VAGAL SCHWANNOMA (CASE REPORT)

 
 
Author(s):  DAS ANIRBAN*, CHOUDHURY SABYASACHI, BASUTHAKUR SUMITRA, MUKHOPADHYAY ANGHSUMAN, MUKHERJEE SIDDHARTHA
 
* DEPARTMENT OF PULMONARY MEDICINE, MEDICAL COLLEGE, KOLKATA, WEST BENGAL, INDIA. ADDRESS: C/O MR. PRADIP DAS, PEON PARA, BHATCHALA, NEAR VIDYARTHI GIRLS’ HIGH SCHOOL, SRIPALILI, P.S.: BURDWAN SADAR, BURDWAN, WEST BENGAL, INDIA
 
Abstract: 

Schwannomas are rare neurogenic tumor originating from Schwann cells of the nerve sheath, most frequently encountered type of posterior mediastinal tumors. In most cases, schwannomas are benign, malignant and multiple schwannomas are rare. Histopathologically, the tumor is composed of fascicles of spindle cells, which are strongly positive for S–100 proteins. Surgical resection is a treatment of choice, and prognosis is excellent. Here, we report a case of posterior mediastinal schwannoma in a 20- years old male patient who complained of right-sided back pain and two episodes of massive hemoptysis of recent onset. Contrast enhanced computed tomography (CECT) and magnetic resonance imaging of the chest showed a well circumscribed, heterogeneous mass in the posterior mediastinum, compressing the right lower lobe with widening of intervertebral foramens. CT-guided trucut biopsy revealed spindle cell neoplasm. On immunohistochemistry, tumor cells expressed strong positivity for S–100 protein. Final diagnosis was schwannoma, probably originating from the right vagus nerve. Surgical resection of the encapsulated tumor resulted in the successful recovery, without any recurrence over next one year follow up.

 
Keyword(s): NEUROGENIC TUMOR, POSTERIOR MEDIASTINUM, SCHWANNOMA, SURGICAL RESECTION, TRU-CUT BIOPSY, VAGUS NERVE
 
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