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Paper Information

Journal:   JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS   FEBRUARY 2014 , Volume 9 , Number 1; Page(s) 49 To 54.
 
Paper: 

ANTIOXIDANT AND ANTIFUNGAL ACTIVITY OF EXTRACTS OF THE AERIAL PARTS OF THYMUS CAPITATUS (L.) HOFFMANNS AGAINST FOUR PHYTOPATHOGENIC FUNGI OF CITRUS SINENSIS

 
 
Author(s):  TABTI LEILA, EL AMINE DIB MOHAMMED*, GAOUAR NASSIRA, BOUAYAD SAMIRA, TABTI BOUFELDJA
 
* LABORATORY OF NATURAL AND BIOACTIVE SUBSTANCES, FACULTY OF SCIENCE, DEPARTMENT OF CHEMISTRY, UNIVERSITY OF TLEMCEN, TLEMCEN, ALGERIA
 
Abstract: 

Background: Many medicinal plants from the Lamiaceae family can be easily found in Algeria. These plants have been used as traditional medicines by local ethnic groups. Thymus capitatus is known in Algeria as “Zaatar” and has been commonly used as a spice, and reported to have many biological effects.
Objectives: This paper focused on the assessment of the antioxidant potential and antifungal activity of essential oil and solvent extracts of T. capitatus against the growth of certain fungi.
Materials and Methods: Essential oil, ethanol and hexane extracts of T. capitatus were tested for their antioxidant and antifungal activities. The 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay was used to determine the free radical quenching capacity. Antifungal activity was assessed using the radial growth technique.
Results: DPPH free radical scavenging effect of the extracts was compared with standard antioxidant ascorbic acid and showed significant results. The ethanol extract showed high activity at the concentration of 80 g/mL, but less than the standard ascorbic acid. The essential oil was effective against all the fungi used in the experiment. The highest inhibitory effect on the growth of Aspergillus niger, Aspergillus oryzae, Penicillium digitatum, and Fusarium solani was exhibited by the essential oil at concentrations between 0.1 and 0.5
mg/mL.
Conclusions: These findings demonstrated that ethanol extract obtained from T. capitatus is a potential source of natural antioxidant, while the essential oil extract can be exploited as an ideal alternative to synthetic fungicides for use in the treatment of many fungal phytopathogens.

 
Keyword(s): ANTIOXIDANTS, CITRUS SINENSIS, 2, 2-DIPHENYL-1-PICRYLHYDRAZYL, LAMIACEAE
 
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