Paper Information

Journal:   ARCHIVES OF IRANIAN MEDICINE   JULY 2014 , Volume 17 , Number 7; Page(s) 495 To 500.
 
Paper: 

EGYPTIAN CONCEPT OF RATIONAL IMMUNE MODULATION: NATURE-FRIENDLY LIFESTYLE FOR TAKING ATHERO-PROTECTIVE PHENOTYPE

 
DOI: 

0141707/AIM.0010

 
Author(s):  BEHJATI MOHADDESEH*
 
* HEART FAILURE RESEARCH CENTER, CARDIOVASCULAR RESEARCH INSTITUTE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN, CARDIOVASCULAR RESEARCH CENTER, CARDIOVASCULAR RESEARCH INSTITUTE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

A slightly lower rate of atherosclerosis in some tropical regions such as the Nile delta in Egypt, Saudi Arabia, Yemen and sub-Sahara Africa is associated with evidences of increased helminthic co-infection. Attempts to eradicate helminthic infections led to the shift of immune balance toward T helper 1 cells and their related cytokines. This shift is parallel with atherogenesis and its related complications. Atherosclerosis is a degenerative man-made disease which begins in early life. Thus, preventive strategies should begin at the same time. As an example to follow, living with old friends, adaption of a more nature-friendly lifestyle and «fine immune-modulation» plans from early childhood, like Egyptians, seems a good option. Finally, a proper intentional balance between T helper 1 and 2 cells should be defended and constructed environmentally in the manner compatible with modern hygiene using a soft application of old hygiene. This needs robust understanding of atheroprotective habits in regions with lower burden of atherosclerosis.

 
Keyword(s): ATHEROGENESIS, ATHERO, PROTECTION, HELMINTHES INFECTION, IMMUNE REGULATION, T HELPER CELLS
 
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