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Paper Information

Journal:   IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)   SEPTEMBER 2013 , Volume 15 , Number 9; Page(s) 771 To 775.
 
Paper: 

COCHLEAR DAMAGES CAUSED BY VIBRATION EXPOSURE

 
 
Author(s):  MOUSSAVI NAJARKOLA SEYYED ALI, KHAVANIN ALI*, MIRZAEI RAMAZAN, SALEHNIA MOJDEH, MUHAMMADNEJAD AHAD
 
* DEPARTMENT OF OCCUPATIONAL HEALTH, SCHOOL OF MEDICAL SCIENCES, TARBIAT MODARES UNIVERSITY, TEHRAN, IR IRAN
 
Abstract: 

Background: Many industrial devices have an excessive vibration which can affect human body systems. The effect of vibration on cochlear histology has been as a debatable problem in occupational health and medicine.
Objectives: Due to limitation present in human studies, the research was conducted to survey the influence of vibration on cochlear histology in an animal model.
Materials and Methods: Twelve albino rabbits were experimented as: Vibration group (n=6; exposed to 1.0 m.s-2 r.m.s vertical whole-body vibration at 4-8 Hz for 8 hours per day during 5 consecutive days) versus Control group (n=6; the same rabbits without vibration exposure). After finishing the exposure scenario, all rabbits were killed by CO2 inhalation; their cochleae were extracted and fixed in 10% formaldehyde for 48 hours, decalcified by 10% nitric acid for 24 hours. Specimens were dehydrated, embedded, sectioned 5 ?m thick and stained with Hematoxylin and Eosin for light microscopy observations.
Results: Severely hydro pic degenerated and vacuolated inner hair cells (IHCs) were observed in vibration group compared to the control group. Inter and intracellular edema was appeared in supporting cells (SC). Nuclei of outer hair cells (OHCs) seemed to be pyknotic. Slightly thickened basilar membrane (BM) was probably implied to inter cellular edematous. Tectorial Membrane (TM) was not affected pathologically.
Conclusions: Whole-body vibration could cause cochlear damages in male rabbits, though vibration-induced auditory functional effects might be resulted as subsequent outcome of prolonged high level vibration exposures.

 
Keyword(s): INNER AUDITORY HAIR CELL, COCHLEAR HEARING LOSS, HISTOLOGICAL TECHNIQUE
 
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