Paper Information

Journal:   IRANIAN JOURNAL OF PEDIATRICS   JUN 2014 , Volume 24 , Number 3; Page(s) 313 To 318.
 
Paper: 

PREPREGNANCY MATERNAL WEIGHT AND BODY MASS INDEX OF CHILDREN WITH AND WITHOUT CONGENITAL HEART DISEASE

 
 
Author(s):  GHADERIAN MEHDI*, ABDOL RAHMAN EMAMI MOGHADAM, KHALILIAN MOHAMMAD REZA, RIAHI KOUROSH, GHAEDI HEIDARI FATEMEH
 
* DEPARTMENT OF PEDIATRIC CARDIOLOGY, EMAM HOSEIN MEDICAL, EDUCATIONAL AND RESEARCH CENTER, ESFAHAN UNIVERSITY OF MEDICAL SCIENCES, IRAN
 
Abstract: 

Objective: Congenital heart diseases are among the most frequent major congenital anomalies. One of the suspected reasons for congenital heart defects is overweight and obesity of mother during prepregnancy and pregnancy. We studied the relationship between maternal overweight and obesity and the risk of congenital anomaly.
Methods: All of children with congenital heart defect (164 infants with major nonsyndromic heart disease) referred to our pediatric cardiology clinic or admitted to our ward during 2011-2012 were included in this study. Controls were 158 live-born infants without any major malformations and their mothers. Mothers of these infants were studied for weight, height and body mass index (BMI).
Findings: The most frequent congenital heart disease was ventricular septal defect (39%), patent ductus arteriosus (11%), complete atrioventricular septal defect (10%), pulmonary stenosis (9.1%), and atrial septal defect (8.5%). There was no significant difference between maternal age (P=0.1), weight (P=0.8) and height (P=0.3) in the two groups. The mothers had not significantly higher BMI than that of the control mothers. Compared with underweight (BMI<18.5) and normal weight women (OR: 1.24, 95%CI: 0.40-3.89), overweight (OR: 0.98, 95%CI: 0.31-3.10) and obese women (OR: 1.16, 95%CI: 0.34-4.00) were not more likely to have an infant with a congenital heart defect.
Conclusion: This study suggests that there may not be a relation between maternal BMI and having a child with congenital heart defect.

 
Keyword(s): CONGENITAL HEART DEFECTS, MATERNAL OBESITY, MATERNAL OVERWEIGHT
 
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