Paper Information

Journal:   IRANIAN JOURNAL OF PUBLIC HEALTH   AUGUST 2014 , Volume 43 , Number SUPPLEMENT 2; Page(s) 61 To 61.
 
Paper: 

EVALUATION OF ASSOCIATION BETWEEN CHLAMYDOPHILA PNEUMONIAE AND ATHEROSCLEROTIC PLAQUES IN CORONARY ARTERY DISEASE PATIENTS WITH ABNORMAL ANGIOGRAPHY

 
 
Author(s):  IRANPOUR DARIYUSH, ABBASI FARHAD, MIRZAE KAMRAN, MOHAMMADZADEH NAHID, RAISI ALIREZA
 
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Abstract: 

Background: The role of Chlamydophila pneumonia in pathogenesis of atherosclerosis is one of the most important discussions in coronary artery diseases.
Methods: In this study, the relationship between Chlamydophila pneumoniae seropositivity and atherosclerotic plaque was evaluated among two groups; one group with significant coronary stenosis and one group with normal coronary angiography. Serum Chlamydophila pneumonia IgM and IgG were evaluated and compared in case and control groups.
Results: The IgM and IgG antibodies seropositivity rates were not statistically different between case and control groups, although the rate of positivity was more in case group.
Conclusion: The results of our study could not make a correlation between Chlamydophila pneumonia infection and atherosclerotic plaque or coronary artery stenosis neither in acute present nor in past chronic infection. Studies that are more precise are needed to clarify the probable inflammatory cascade that starts with Chlamydophila pneumonia infection and ends with development of atherosclerotic plaque.

 
Keyword(s): CHLAMYDOPHILA PNEUMONIA, ATHEROSCLEROSIS, ANGIOGRAPHY, INFECTION
 
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