Paper Information

Journal:   HEPATITIS MONTHLY   MAY 2014 , Volume 14 , Number 5; Page(s) 0 To 0.
 
Paper: 

BRIEF REPORT: DISTRIBUTION OF HCV GENOTYPES IN THE POPULATIONS OF INMATES IN POLISH PRISON POTULICE AND PATIENTS HOSPITALISED IN BYDGOSZCZ

 
 
Author(s):  TYCZYNO MALGORZATA*, HALOTA WALDEMAR, NOWAK WOJCIECH, PAWLOWSKA MALGORZATA
 
* DEPARTMENT OF INFECTIOUS DISEASES AND HEPATOLOGY, NICOLAUS COPERNICUS UNIVERSITY, BYDGOSZCZ, POLAND
 
Abstract: 

Background: According to many studies, one of the social groups with high rate of HCV infections are prisoners.
Objectives: The aim of the study was to determine and compare the genotypes distribution among prisoners and patients of hospital.
Patients and Methods: HCV genotypes among prisoners (281 inmates) and patients of hospital (1415 patients) were determined in years 2002-2012. HCV genotypes were determined in 2002-2005 with INNO-LiPA HCV II test (Innogenetics, Gent, Belgium) and since 2006 with LINEAR ARRAY assay (Roche, Mannheim, Germany), after isolation and amplification of the material with COBAS AMPLICOR v 2.0 (Roche, Mannheim, Germany).
Results: The most frequent HCV genotype among inmates was genotype 3, which was detected in169 of 281 patients (60.1%). Most frequent genotype among hospitalized was genotype 1, which was found in 1127 cases (79.6%). Comparing the results of prisoners with a group of patients with HIV/HCV co-infection gave similar results. In both groups most frequent was genotype 3 (respectively 60.1 and 45.5%). However, most prisoners in this study (96%) were HIV-negative.
Conclusions: The current study shows that the predominant HCV genotype among inmates from prison in Potulice is genotype 3.

 
Keyword(s): HEPATITIS C, HCV, PRISON
 
References: 
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