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Paper Information

Journal:   IRANIAN JOURNAL OF PUBLIC HEALTH   AUGUST 2014 , Volume 43 , Number SUPPLEMENT 2; Page(s) 57 To 57.
 
Paper: 

THE ROLE OF BACTERIAL INFECTION IN DEVELOPMENT OF MENTAL DISORDERS

 
 
Author(s):  DABIRI HOSSEIN, KHOSHNOOD SAEED*, HEIDARY MOHSEN, YOUSEFI NEDA, ROSHANI MAHDANE
 
* DEPARTMENT OF MEDICAL MICROBIOLOGY, SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Background: So far, there is no report considering Meta analysis study on microorganism and mental disorders. The purpose of this study was to investigate the psychological effects caused by bacterial infections.
Methods: In the current Meta-analysis study, we used keywords such as mental disorders, mental diseases and microorganism/ depression and search engines SID, Iranmedex, Web of Science, PubMed and Google scholar. We did comprehensive data collection. All articles with no row data were excluded. According to inclusion, criteria out of 24 articles18 studies data were analyzed using Meta analysis software.
Results: Considering 34 studies, overall 7041 patient with diverse mental disorders and control have been studied. In these populations, Chlamydia spp, E. coli, Brucella spp. Streptococcus group A, Mycoplasma spp, and Mycobacterium, Helicobacter pylori have been studied. Mycobacterium spp. (33% case vs. 9.8% control), Streptococcus group A (38.% case vs. 14.6% control), E. coli (17% case vs. 4.5% control), Brucella spp, (24% case vs 10.2 control) and H. pylori (16.5% case vs. 5.2 control) contributed to development of mental disorders while Chlamydia spp (13.8% case vs. 13.6% control) did not show any association with psychological disorders. The most mentioned diseases contributing to these microorganisms were schizophrenia, depression and autisms.
Conclusion: According to the psychological impact of the disease on people lives, the role of bacteria in causing these diseases is very important as they can transmit from person to another. Considering the role of Mycobacterium spp, E.coli, Brucella spp. Streptococcus group A, and H. pylori in development of mental diseases, we suggest that an early detection and a rapid elimination of the bacteria can be helpful in prevention of mental illness.

 
Keyword(s): MENTAL DISORDERS, BACTERIAL INFECTION, SCHIZOPHRENIA, DEPRESSION AND AUTISMS
 
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