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Paper Information

Journal:   ARCHIVES OF PEDIATRIC INFECTIOUS DISEASES   JANUARY 2015 , Volume 3 , Number 1; Page(s) 1 To 5.
 
Paper: 

MULTIFOCAL DACTYLITIS AS A CONSEQUENCE OF BACILLUS CALMETTE-GUERIN VACCINATION IN A PATIENT WITH SEVERE COMBINED IMMUNODEFICIENCY: A CASE REPORT

 
 
Author(s):  KARIMI ABDOLLAH, RAFIEI TABATABAEI SEDIGHEH, AMANATI ALI*, GHOROUBI JAVAD, KARAMI MOHSEN
 
* PEDIATRIC INFECTIONS RESEARCH CENTER, DEPARTMENT OF PEDIATRIC INFECTIOUS DISEASES, MOFID CHILDREN’S HOSPITAL, SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IR IRAN
 
Abstract: 

Introduction: Bacillus Calmette-Guerin (BCG) vaccine, a live attenuated Mycobacterium bovis strain, is administrated to all newborn infants in endemic regions according to the current World Health Organization (WHO) recommendation.
Case Presentation: We report a 10-month-boy who was a known case of severe combined immunodeficiency (SCID) admitted with multifocal fusiform painful swelling in his hands. He had undergone bone marrow transplantation 7 weeks before admission. Multidisciplinary management was done to treat this rare post-transplant occurrence of Bacillus Calmette-Guerin complication.
Conclusions: BCG vaccination administrated routinely in Iran, given that of no screening program for primary immune deficiency currently achieved in our country, exact attention to reschedule of immunization programs in suspicious newborn (with primary immune deficiency) always is necessary and is one of the most effective strategy to prevent BCG complication.

 
Keyword(s): BACILLUS, SEVERE COMBINED IMMUNODEFICIENCY, BONE MARROW TRANSPLANTATION
 
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