The Pigeonhole Of Occult Hepatitis B (Review Article)

DINDOOST PAYAM; CHIMEH NARGES; HOLLINGER BLAIN F.; SABERFAR ESMAEIL; NOROUZI MEHDI; JAZAYERI SEYED MOHAMMAD

Paper Information


Journal: ACTA MEDICA IRANICA 2014 , Volume 52 , Number 8; Page(s) 0 To 0.

Paper: The Pigeonhole Of Occult Hepatitis B (Review Article)



Author(s): Dindoost Payam, Chimeh Narges, Hollinger Blain F., Saberfar Esmaeil, Norouzi Mehdi, Jazayeri Seyed Mohammad*

* DEPARTMENT OF VIROLOGY, FACULTY OF PUBLIC HEALTH, TEHRAN UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN

Abstract: Occult Hepatitis B (OHB), or persistent hepatitis B virus (HBV) viremia in surface-antigen-HBsAg-negative patients, has been recognized as a medical concern during the last decade. The exact magnitude, pathogenesis and clinical relevance of OHB are unclear. This review organizes the published data on OHB and presents an overview of the current hypotheses on OHB’s pathogenesis and clinical relevance. Many explanations have been offered for the pathogenesis of OHB, ranging from the inability of standard immunoassays to diagnose OHB to the involvement of the versatile virus-host factors Also, special care should be taken regarding the diagnosis of OBH. It seems that both shared viral-host factors are involved in the pathogenesis of OBH. Further molecular studies on cohort patients group need to explore such association.

Keyword(s): OCCULT HEPATITIS B INFECTION, HBV DIAGNOSIS, HBSAG MUTATIONS



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+ Click to Cite. APA: Copy DINDOOST, P., & CHIMEH, N., & HOLLINGER, B., & SABERFAR, E., & NOROUZI, M., & JAZAYERI, S. (2014). THE PIGEONHOLE OF OCCULT HEPATITIS B (REVIEW ARTICLE). ACTA MEDICA IRANICA, 52(8), 0-0. https://www.sid.ir/en/journal/ViewPaper.aspx?id=410232 Vancouver: Copy DINDOOST PAYAM, CHIMEH NARGES, HOLLINGER BLAIN F., SABERFAR ESMAEIL, NOROUZI MEHDI, JAZAYERI SEYED MOHAMMAD. THE PIGEONHOLE OF OCCULT HEPATITIS B (REVIEW ARTICLE). ACTA MEDICA IRANICA. 2014 [cited 2022August08];52(8):0-0. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=410232 IEEE: Copy DINDOOST, P., CHIMEH, N., HOLLINGER, B., SABERFAR, E., NOROUZI, M., JAZAYERI, S., 2014. THE PIGEONHOLE OF OCCULT HEPATITIS B (REVIEW ARTICLE). ACTA MEDICA IRANICA, [online] 52(8), pp.0-0. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=410232.

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The Pigeonhole Of Occult Hepatitis B (Review Article)